CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020656
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CUE domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Cuedc2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
253DNQVVSTKGERFKDVubiquitination[1]
269NPEAEEMKATYINLKubiquitination[1]
276KATYINLKPARKYRFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation (By similarity). 
Sequence Annotation
 DOMAIN 141 184 CUE.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MELERIVGSA LLTFVQAHLP EADLSGLDEV IFSYVLGVLE DLGPSGPSEE NFDMEAFTEM 60
MEAYVPGFAH IPRGIIGDMM QKLSVQLSDA RNKENLHPQS SCVQGQVPIF PETPRQAEKL 120
EEESRPPAAP GNTLDEAAAA EELPGVDVLL EVFPTCSMEQ AQWVLAKARG DLEEAVHMLV 180
EGKEEGPPGW DGPSQDLPRR LRGPQKDDLK SFILQKYMMV DRAEDQKTHR PMAPKEAPKK 240
LIRYIDNQVV STKGERFKDV RNPEAEEMKA TYINLKPARK YRFH 284 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 
Interpro
 IPR003892; CUE. 
Pfam
 PF02845; CUE 
SMART
  
PROSITE
 PS51140; CUE 
PRINTS