CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cylicin-1 
Protein Synonyms/Alias
 Cylicin I; Multiple-band polypeptide I 
Gene Name
 CYLC1 
Gene Synonyms/Alias
 CYL; CYL1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
389NDSRNLKKASKNDDKacetylation[1]
396KASKNDDKKKDAKKIacetylation[1]
397ASKNDDKKKDAKKITacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. 
Sequence Annotation
 REPEAT 278 305 1.
 REPEAT 306 342 2.
 REPEAT 343 379 3.
 REPEAT 380 417 4.
 REPEAT 418 453 5.
 REPEAT 454 491 6.
 REPEAT 492 531 7.
 REPEAT 532 553 8.
 REGION 532 553 8 X approximate tandem repeats.  
Keyword
 Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Differentiation; Polymorphism; Reference proteome; Repeat; Spermatogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 651 AA 
Protein Sequence
MSLPRLLKVN IRTYDNSIPI SESSRKSWNQ KHFALTFPKP LQRGTNDKSR PLKSQITVTR 60
HDKRKLEEGQ KPAHKWIRHS FRKILQWPPI YTAAREQTPF RHLYTSKTHL KKAEYKKSKD 120
EKGGTPLKKD SKKKGGSYAT NPESKQIVEE KTKRQNEADK TPLKSSHENE QSKKSKSSSE 180
TNPESQNSKT VSKNCSQKDK KDSKNSKKTN TEFLHTKNNP KKDLKRSKTS NDPISEICSE 240
NSLNVDFLML VGQSDDESIN FDAWLRNYSQ NNSKNYSLKY TKYTKKDTKK NAKKSSDAES 300
EDSKDAKKDS KKVKKNVKKD DKKKDVKKDT ESTDAESGDS KDERKDTKKD KKKLKKDDKK 360
KDTKKYPEST DTESGDAKDA RNDSRNLKKA SKNDDKKKDA KKITFSTDSE SELESKESQK 420
DEKKDKKDSK TDNKKSVKND EESTDADSEP KGDSKKGKKD EKKGKKDSKK DDKKKDAKKN 480
AESTEMESDL ELKKDKKHSK EKKGSKKDIK KDARKDTEST DAEFDESSKT GFKTSTKIKG 540
SDTESEESLY KPGAKKKIDE SDGTSANSKM EGLESKRGFR MSSKKTTFNE KGEKASTGRV 600
PPSREKPPLP ACEPSLPSPK VRRLCWCKMP PPPPKPRYAP LPEAPWIHKL L 651 
Gene Ontology
 GO:0043159; C:acrosomal matrix; IDA:MGI.
 GO:0033150; C:cytoskeletal calyx; IEA:UniProtKB-SubCell.
 GO:0005856; C:cytoskeleton; NAS:UniProtKB.
 GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
 GO:0005198; F:structural molecule activity; NAS:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; NAS:UniProtKB. 
Interpro
 IPR026189; CYLC. 
Pfam
  
SMART
  
PROSITE
  
PRINTS