UniProt Accession

 NHLC3_HUMAN; Q5JS37; B2RTZ2; B4DTL0; Q69YI9 

Genbank Protein ID

 AK300260; AL445590; CH471075; CH471075; BC140877; BC140878; AL833329 

Genbank Nucleotide ID

 BAG62022.1; CAI40978.1; EAX08613.1; EAX08615.1; AAI40878.1; AAI40879.1; CAH10395.1 

Protein Name

 NHL repeat-containing protein 3 

Protein Synonyms/Alias

  

Gene Name

 NHLRC3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
86	QRGDNIPKILVFTED	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 REPEAT 47 93 NHL 1.
 REPEAT 150 196 NHL 2.
 REPEAT 200 243 NHL 3.
 REPEAT 294 338 NHL 4.
 CARBOHYD 32 32 N-linked (GlcNAc...) (Potential).
 CARBOHYD 101 101 N-linked (GlcNAc...) (Potential).
 CARBOHYD 206 206 N-linked (GlcNAc...) (Potential).
 CARBOHYD 278 278 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Glycoprotein; Polymorphism; Reference proteome; Repeat; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 347 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. 

Interpro

 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR001258; NHL_repeat.
 IPR013017; NHL_repeat_subgr. 

Pfam

 PF01436; NHL 

SMART

  

PROSITE

 PS51125; NHL 

PRINTS