| Tag | Content |
|---|
| CPLM ID | CPLM-010979 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidyl-prolyl isomerase CWC27 |
Protein Synonyms/Alias | PPIase CWC27; Complexed with CEF1 protein 27; Rotamase CWC27 |
Gene Name | CWC27 |
Gene Synonyms/Alias | CYP7; YPL064C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 211 | DDDGDVQKLKPRKRM | acetylation | [1] | | 289 | ETLAMLSKFQERIKN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity). |
Sequence Annotation | DOMAIN 9 159 PPIase cyclophilin-type. |
Keyword | Complete proteome; Cytoplasm; Isomerase; mRNA processing; mRNA splicing; Nucleus; Reference proteome; Rotamase; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 301 AA |
Protein Sequence | MSSNIEPQTT AKCILYTTKG NIAIELWAKE CPETCKRFLS MLSDGTFTNG EFKELKPTQW 60
LMFNANSTGE YRTVAEEKNP RIRFNRDGLL GWDRRRNTWF ITVLADSKHV LNDCNVFGKI 120
VGKSIYIFRE ILGGEIEASS RDNDVKRFMY PAVLKDVEIT IPFFEDIFGS KRRLEDNEKK 180
EQEPAKKLVK SAKVKMVYED EQEDDDGDVQ KLKPRKRMIL PAWIKDDSRS EGIKLDASLD 240
QPQEALIREK TELHDNVDEA TTKETESQEN IKEEPMDKRE RETLAMLSKF QERIKNKNIL 300
K 301 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005684; C:U2-type spliceosomal complex; IDA:SGD. GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0006457; P:protein folding; IEA:UniProtKB-KW. GO:0000413; P:protein peptidyl-prolyl isomerization; IEA:GOC. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. |
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