CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023733
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acyl-coenzyme A thioesterase 9, mitochondrial 
Protein Synonyms/Alias
 Acyl-CoA thioesterase 9; Acyl-CoA thioester hydrolase 9 
Gene Name
 ACOT9 
Gene Synonyms/Alias
 CGI-16 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68TNWRDHVKAMEERKLubiquitination[1]
74VKAMEERKLLHSFLAubiquitination[1]
82LLHSFLAKSQDGLPPubiquitination[1]
147HNKIHSAKMSPLSIVubiquitination[1]
259FSSTSLLKMAPSAEEubiquitination[1]
281FLSTLDPKTISFRSRubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs. 
Sequence Annotation
 MOD_RES 103 103 N6-acetyllysine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Hydrolase; Mitochondrion; Polymorphism; Reference proteome; Serine esterase; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 439 AA 
Protein Sequence
MRRAALRLCA LGKGQLTPGR GLTQGPQNPK KQGIFHIHEA CSSIHVNHVR DKLREIVGAS 60
TNWRDHVKAM EERKLLHSFL AKSQDGLPPR RMKDSYIEVL LPLGSEPELR EKYLTVQNTV 120
RFGRILEDLD SLGVLICYMH NKIHSAKMSP LSIVTALVDK IDMCKKSLSP EQDIKFSGHV 180
SWVGKTSMEV KMQMFQLHGD EFCPVLDATF VMVARDSENK GPAFVNPLIP ESPEEEELFR 240
QGELNKGRRI AFSSTSLLKM APSAEERTTI HEMFLSTLDP KTISFRSRVL PSNAVWMENS 300
KLKSLEICHP QERNIFNRIF GGFLMRKAYE LAWATACSFG GSRPFVVAVD DIMFQKPVEV 360
GSLLFLSSQV CFTQNNYIQV RVHSEVASLQ EKQHTTTNVF HFTFMSEKEV PLVFPKTYGE 420
SMLYLDGQRH FNSMSGPATL RKDYLVEP 448 
Gene Ontology
 GO:0005739; C:mitochondrion; ISS:HGNC.
 GO:0003986; F:acetyl-CoA hydrolase activity; ISS:HGNC.
 GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.
 GO:0006637; P:acyl-CoA metabolic process; ISS:HGNC. 
Interpro
 IPR006683; Thioestr_supf. 
Pfam
 PF03061; 4HBT 
SMART
  
PROSITE
  
PRINTS