UniProt Accession

 LRC28_HUMAN; Q86X40; A8KA22; Q6UY49; Q6ZSS6 

Genbank Protein ID

 AY358082; AK127177; AK292887; AC022819; AC037479; CH471101; BC047306 

Genbank Nucleotide ID

 AAQ88449.1; BAC86870.1; BAF85576.1; EAX02243.1; AAH47306.1 

Protein Name

 Leucine-rich repeat-containing protein 28 

Protein Synonyms/Alias

  

Gene Name

 LRRC28 

Gene Synonyms/Alias

 UNQ436/PRO867 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*MASELCKTISVARL	ubiquitination	[1]
18	VARLEKHKNLFLNYR	ubiquitination	[1]
36	HFPLELLKDEGLQYL	ubiquitination	[1]
134	PPEVGDLKELQTLDI	ubiquitination	[2]
217	VDNNIHLKGLPSYLY	ubiquitination	[1]
226	LPSYLYNKVIGCSGC	ubiquitination	[1]
243	PIQVSEVKLLSFSSG	ubiquitination	[1]
261	VFLPAEVKAIGTEHD	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 REPEAT 16 36 LRR 1.
 REPEAT 42 63 LRR 2.
 REPEAT 66 87 LRR 3.
 REPEAT 89 110 LRR 4.
 REPEAT 112 133 LRR 5.
 REPEAT 135 156 LRR 6.
 REPEAT 158 180 LRR 7.
 REPEAT 181 202 LRR 8.
 REPEAT 204 226 LRR 9.  

Keyword

 Alternative splicing; Complete proteome; Leucine-rich repeat; Polymorphism; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 367 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR003591; Leu-rich_rpt_typical-subtyp. 

Pfam

  

SMART

 SM00369; LRR_TYP 

PROSITE

  

PRINTS