CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016258
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Juxtaposed with another zinc finger protein 1 
Protein Synonyms/Alias
 TAK1-interacting protein 27; Zinc finger protein 802 
Gene Name
 JAZF1 
Gene Synonyms/Alias
 TIP27; ZNF802 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47TDPRVLEKQELQQPTubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
 Potential transcription factor. 
Sequence Annotation
 ZN_FING 12 37 C2H2-type 1.
 ZN_FING 173 198 C2H2-type 2.
 ZN_FING 208 230 C2H2-type 3; degenerate.  
Keyword
 Alternative splicing; Chromosomal rearrangement; Complete proteome; Metal-binding; Nucleus; Proto-oncogene; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MTGIAAASFF SNTCRFGGCG LHFPTLADLI EHIEDNHIDT DPRVLEKQEL QQPTYVALSY 60
INRFMTDAAR REQESLKKKI QPKLSLTLSS SVSRGNVSTP PRHSSGSLTP PVTPPITPSS 120
SFRSSTPTGS EYDEEEVDYE ESDSDESWTT ESAISSEAIL SSMCMNGGEE KPFACPVPGC 180
KKRYKNVNGI KYHAKNGHRT QIRVRKPFKC RCGKSYKTAQ GLRHHTINFH PPVSAEIIRK 240
MQQ 243 
Gene Ontology
 GO:0017053; C:transcriptional repressor complex; IDA:MGI.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS