CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003361
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative aga operon transcriptional repressor 
Protein Synonyms/Alias
  
Gene Name
 agaR 
Gene Synonyms/Alias
 yhaW; b3131; JW3100 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
57NDLAFLEKQGIAVRAacetylation[1]
85VEPSVEDKSALNTAMacetylation[1]
225IVVTDSSKFNRSSLHacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism. 
Sequence Annotation
 DOMAIN 15 70 HTH deoR-type.
 DNA_BIND 32 51 H-T-H motif (Potential).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 269 AA 
Protein Sequence
MSNTDASGEK RVTGTSERRE QIIQRLRQQG SVQVNDLSAL YGVSTVTIRN DLAFLEKQGI 60
AVRAYGGALI CDSTTPSVEP SVEDKSALNT AMKRSVAKAA VELIQPGHRV ILDSGTTTFE 120
IARLMRKHTD VIAMTNGMNV ANALLEAEGV ELLMTGGHLR RQSQSFYGDQ AEQSLQNYHF 180
DMLFLGVDAI DLERGVSTHN EDEARLNRRM CEVAERIIVV TDSSKFNRSS LHKIIDTQRI 240
DMIIVDEGIP ADSLEGLRKA GVEVILVGE 269 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IDA:EcoCyc.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IMP:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR014036; DeoR_C.
 IPR001034; HTH_DeoR_N.
 IPR018356; Tscrpt_reg_HTH_DeoR_CS.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00455; DeoRC
 PF08220; HTH_DeoR 
SMART
 SM00420; HTH_DEOR 
PROSITE
 PS00894; HTH_DEOR_1
 PS51000; HTH_DEOR_2 
PRINTS