CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001025
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein phosphatase 1 regulatory subunit 11 
Protein Synonyms/Alias
 Hemochromatosis candidate gene V protein; HCG V; Protein phosphatase inhibitor 3 
Gene Name
 PPP1R11 
Gene Synonyms/Alias
 HCGV; TCTE5 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
59HMGRRSSKCCCIYEKubiquitination[1]
66KCCCIYEKPRAFGESacetylation[1]
66KCCCIYEKPRAFGESubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Inhibitor of protein phosphatase 1. 
Sequence Annotation
 MOD_RES 73 73 Phosphoserine.
 MOD_RES 74 74 Phosphoserine.
 MOD_RES 75 75 Phosphothreonine.
 MOD_RES 77 77 Phosphoserine.
 MOD_RES 109 109 Phosphothreonine.  
Keyword
 Complete proteome; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 126 AA 
Protein Sequence
MAEAGAGLSE TVTETTVTVT TEPENRSLTI KLRKRKPEKK VEWTSDTVDN EHMGRRSSKC 60
CCIYEKPRAF GESSTESDEE EEEGCGHTHC VRGHRKGRRR ATLGPTPTTP PQPPDPSQPP 120
PGPMQH 126 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. 
Interpro
 IPR011107; PPI_Ypi1. 
Pfam
 PF07491; PPI_Ypi1 
SMART
  
PROSITE
  
PRINTS