CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013567
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fibrous sheath-interacting protein 2 
Protein Synonyms/Alias
  
Gene Name
 FSIP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
4319IVARLLSKIFSPKHNubiquitination[1]
5747KNISAKEKEEEEREKacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 6907 AA 
Protein Sequence
MELYLGACSK PAKVAVTKTV ASVLAADTQQ CRDGVHKTHF AGVGPAQLLD LPLGVKLPVI 60
PGSNAVFYTT NFGEKLFRPS YGFNLTDPYC RLLENQYKSL HDPHLKAYYK RKDILKRLKK 120
GGYITSNNKV VCTLRELNKY RQYLTSLKLD FERNYIKEQR ILAKQLHNIP ENNQIPQHCD 180
VAQVQNWLLK EGTESIKDQE RLMRHRYLDM ISRKLEQLER TAEEQRLFLM DREERRQREH 240
TRRKLTLRRK IEEEWKTKEM LLLTRMAEDV KREERIEEQQ HRNREESDRK KQDLLEKKMA 300
YHLQKMQDTG FNGEDIGKNT FKYRGQDGTH ASPKNKKKTS EDIMLVYPAG DQNTYKETHG 360
HTANAAHQRQ NSSNNFTKKN SASVVYQADV QDNGINQKRD GMVSKNSSIF DDRGGINISG 420
QGSIISAQVS PTRNFSRVSQ AFLDPSKEEK ETNADWDGRP TKRSSYLCES GPQAHATDPG 480
IFSSPVYTNM QQNLLQNCLQ EKVTSEELNI IIQNVMTWVV ATVTSILYPA ITKYEKRLQN 540
NTYPVSDDSI LSSDSSSFCS TCSEDFTYRS YTSATTKTFQ AEPCAFVVDT SVRRPTTPIK 600
PPPAHVEKTV VGKTCHIKGQ SIISKHKYNK TNLLYSYPKL RSCKSDSHLL ASFETGTKKS 660
KDATTETDSL GSSLHCDKTA KAMDEMKNLK NVFVNFKCYL KGETEVILES ILREIMSDLT 720
QAIPSLSSVT AEVFVEQCER EKEILLSNAH IPSVASEIVE NMLEKLESAV EKKCVEMFSQ 780
DLSVDIKPSL AASDELLTSS NGKPLKNSMP HTLDPMCDIA EDMVHAILEK LMTLVSFKQN 840
EFLHLKDTNK LSCQQHKTDP ICMFLQRAGK NKSSLESDEA SLIVNEEVQN LISNIFSQSS 900
LVAYIEEAIN AILGYIQTEL NNERIIASEE TVVLLQLLED ILFQLHQEPV NESFQKSRQP 960
RISSPSDTKE KYRLTGTRLS NSPRSGRPFP PINVPGMVLY SDDENEEIDN IVKNVLDSTF 1020
KDEKVKSQEQ IPNHWFTKGN TCFECKRNIK PPTKPGSRSK AAFHDWELKT EPPSTNHEDI 1080
LKKKLSSNKD ISTFSQDQKH QIEKASENIV TSILKEMLKD ISSVPFGHLD SKTGSEASVL 1140
VSEKPQGLSH QEWIDQMFSV SEISTVAQEI TDSVLNILHK ASNYISNTTK SSISSSVHQI 1200
SLHNSDTEHI VKEAPNKYPL KTWFDSEKKM KYLSLFDVDP EKPPWLKSGK SEPKPVDDIN 1260
DKIIRTIFKR LKSFICPKLH MGFKSSLRSQ LSKYTAKIVN IVLCAIQNEL ELHKENLNLR 1320
EIDHTKSLTD KGFFANTDKK LESLVTSIDD DILASPLLTC IYDMLLSSEN AHQRSISLSS 1380
RKPKSATDSV DVQSILPNRQ DKKSFHKYLA TPCTHHSVNG GNHIKENAKL QVLERIGETL 1440
HEMLSKLLGT HLHSQLSCSQ QSREMTNKNQ KMAAALQSNI QLISKAILDY ILAKLCGVDM 1500
DTSFASCGLK AISESLDIDN PSFASIIEKM AKSTKIISSI VSRRVQEDNK EETKSKAKPV 1560
APVSSKTPST KEMHPNKLKA VASDILNMVF AKLEGFANGH LEILGAINDG NKKSNKIGWE 1620
YESTNISRDT HEASFLSALY MHAKKVSSAI LKVIQTELNV TSSDLKTSVE NPPPETQILK 1680
YVVKLILDAV SSDMFNEMES EGGGIETYRY RPTYGSLPGG AESDSFLEDD AYTAKKIIDE 1740
RSPQREEVKT RSLKQWALEK TLNKIEVKLK EPHISPIAPI IRNILNEIFQ STLINQLNVL 1800
SLSHSNFNGM PHNVDEPTPQ TSVQFMDKMM DPLLSEADIT IVTDNIVRTV FHKLYSAAMT 1860
ERNVRENRYK TITFSANVSS HEHTYKGKSS VTALDENPCT FQSRFSVADK ETKVNLAEDI 1920
VQAILTNLET FATSKVKSLF YSQVNFTVPV ALPIQQDHST LSKALSAKDS YSDEQFSCCS 1980
VDHTKSGKTN LCQLSLSKLN TYALQVARRN LQGIKQELDK ERENPFLTHD IGISESIASQ 2040
IVNALLDIIS RKGKCDKNSS DKEIDLDQQK GVIEKLLNET KYRKVLQLQI QDTIEGILCD 2100
IYEKTLFQNN LSFATPTLKC SIADKHSEEN SEMFMEGANK IIPKLSVPKS DVILISNDIV 2160
NIVLHNLSSA ATLVINAKNP TSARLPLTFC DTFPKIDCQQ PLKGSKTERK TERFSYSRNQ 2220
KSAYADDNQI TVVEKEDTQK SATDSCEENA NFITKTIFKR LESFATERID SLITLAFQSK 2280
EKSFVIPELE NCKQNDSIFY DSSQVESDVN VLKISATETI LSQELTDFTF VGRREKLGST 2340
IHLSQARLKT YADVIASAIL KLIKNDLDLE IQKIYPYQNN ILFQENIIVS EIVDSMLKML 2400
DDKRSVKEIC FNSKENSNFS QLALSNEILL GHKEKERSTK QSLFTKYPLE QNQMILENKR 2460
QIIVLEEIFM RNGESKNKEK GELLIAVEEL LNKLYQRVRE VTGHLPPLNE TANFISNSKI 2520
KTSDTTQKNS FQSHINSVAN DIVESVLGKM YLVVVTSLYE NNKSRTEVEI SDHNDSLLMK 2580
PLRFRETKQA GKISNSPRYA ISQAYSYVDS QNISVMENTL LPYLPLQVKK DLIQMVLNKI 2640
TNFVSLPLKV SPKDNPKPCF KAHLKTRSKI TTLPKFTKKT HLGLSAAKAK SKTKLGPGEK 2700
TLKDSRSKTA IGLSHIMSAG DAKNLLDTKL PTSELKIYAK DIIINILETI VKEFGKVKQT 2760
KALPSDQIIA AGKIVNTVLQ ELYVTNNCNL AYPMKSSHLR LSQGNIGTGS LPKQQACFYL 2820
ENVSSQLEHI FPREGIFKKL FDKWQTESND KENEKCKLLM IAENVLTEIS IKAKELEYSL 2880
SLLNLPPLEN CESRFYNHFK GASTRAEDTK AQINMFGREI VEMLLEKLQL CFLSQIPTPD 2940
SEETLSNSKE HITAKSKYGF PNKHSLSSLP IYNTKTKDQI SVGSSNQIVQ EIVETVLNML 3000
ESFVDLQFKH ISKYEFSEIV KMPIENLSSI QQKLLNKKML PKLQPLKMFS DKSESNTINF 3060
KENIQNILLR VHSFHSQLLT YAVNIISDML AVIKNKLDNE ISQMEPSSIS ILKENIVASE 3120
IIGTLMDQCT YFNESLIQNL SRESLFQGAE NAYTVNQVEL ATNMKMFTSK LKEGSLGINP 3180
SQVSKTGFVF CSDEDMKEKY RVSSDLPTSV RSSVEDTVKN SEPTKRPDSE TMPSCSTRNK 3240
VQDHRPRESN FGSFDQTMKG NSYLPEGSFL QKLLRKASDS TEAALKQVLS FIEMGKGENL 3300
RVFHYENLKP VVEPNQIQTT ISPLKICLAA ENIVNTVLSS CGFPSQPHTN ENREIMKPFF 3360
ISKQSSLSEV SGGQKDNEKS LLRMQDKKIN YIPEEENENL EASREDSSFL QKLKKKEYPK 3420
IETVKEVEAF TFADHEMGSN EVHLIARHVT TSVVTYLKNF ETTVFSEEKM SVSTWSRKKY 3480
ESKQFLRNIY DDSSIYQCCE HLTESVLYHL TSSISDGTKK GREKEKAWEI QEATFSKIIS 3540
IHSQVFESRS ISIGELALCI SEIIIKILFN NKIIQADIAQ KMVAIPTKYT YCPGIVSGGF 3600
DDLFQDLLVG VIHVLSKEIE VDYHFESNVR NKSFSMHRNN SVPLCNKINR QASPRDWQFS 3660
TQQIGQLFQK NKLSYLACKL NSLVGNLKTS ESKEVVNKVF NIVSDLFSPD ECLDTGMDSG 3720
KIQRTYFYSS NNEQPNSILT NNLQLSSKSV FLLNVVCEKL IRILLEECTS TAFPDKGSVS 3780
EETSAEECQL LKMLQSVEDG KSDYRKGGMD CECLQVDYMS DLLENVAEID QDLLTSDSML 3840
TIISHSLVKS LMDKLSHSIQ QAPESLPFAN KHLNYRTREI QSSFIKARKS ELIELGQSKS 3900
SLELRSYDSN SLTVSLNNPS VVSSKIQAPF NKHCAVKSSS VSPFERQRTK EMDKVAIHNK 3960
LHQEGIYAGV YSATFLEGII SELFFNLSMS LWGKNKNITV SWLNEMNTLF VNNVVNEFNN 4020
AQVTVLRNAE ERLCFPPVHT ETVSKIVDSV YYDVLQQYEL KVACGNNPVY DNASIAEQIT 4080
NGILLEILDY KLPSCFKEHL IPHSYYPLKP EIILQKLQSN LTEFTSLPRS SSDYSTMLSH 4140
SFLEDVIRRL LSQLIPPPIT CSSLGKKYLM SSDFNEMSTC IINKVMSAIS KHKIWFTIYD 4200
NQYLYTGKNL QKMVDSVYCN ILQMSDSLVS IQKSIVSRSP IMIDQIASFI IQEIIENHLQ 4260
PFLSGEVLCH PRTPLDPVST IVTQVLSEVI ESHRPQKQSP LDIHLDSFVR EIVARLLSKI 4320
FSPKHNTEIE LKNMTQRIVN SINRHFNKAK IHILYDDKEQ AFFSFNTDIV DELATSVYRN 4380
ALKQHGLDLA VDKESEDSGI FVENITNLIV AAISDYLLHP LFSGDFSAST YSNSVAENIV 4440
QDILSNISKS TEPSQSVPLY NTLLPYTFLE DMIRVLLSKL FSSASSLVLN RDTQKDISRV 4500
NFNDIASNLV SDIRMKVSQH EIRFSKEEEE TKFIYSEDDI QHLVDSVFAN VVQTSGSQES 4560
AVQNITSSND ILIDRIAGFI IKHICQKHLQ PFVSGKSLSS SDTYFDDERR QLFYTSVYSS 4620
TFLEDVISGV LRKIFHRVVG IVQTKSIRDS EDELFEKAEE LIHLITGEFS KAQVSIIDNT 4680
EERLCLPPVE RDVVKTIVDM VYSKVLQEYE MEVVPNKDFL NDTKTLAARI TNIILAEIFD 4740
FQIHPDLIAN LPFKSHSKLS ANVLIQRVQY DISKSRFQRQ ASTMYTTMLS HSHLEKIVTQ 4800
LTSQISPLNT SAEQSDTTKS DLSNTVIKLI NEIMSIISKH EICIIKYGNK KQSMISAKDI 4860
QSMVDSIYAD LSHSNIYQSI TKDKKSISDI PVSKIASFII KEIFNHHIQS FLSEDKTLLL 4920
AAVDQTYKLK AIDPKQRELS FIVNSSVFLE EVISELLCKI LYAFSHNMLV TENPDRVKLK 4980
LTRIVTTLVN SIVLEFTTSE ILVADNFDKN LCFSERYKEM VQKIVNSVYG KVLDQYKSLI 5040
QIHRVIQSDT ICFGRKIYYL LLEEIYDYQV QSLVSGELES SSYSYPQADN IIRNVLNIIT 5100
KDSHALPPYI TVLPHSLLED MVYRLLGHVF PSTHTENELK EKKFPPDDEF VEAASKLTDE 5160
IIKEISEHEI RLSMAEDNAE SMQLEPIENL VDSICNNILK TSEFQAEVQK DADKKGCSFL 5220
SKLAGFIMKE IMYHHLQPFL HGEESSFSDL SDYDHVSELA KSGKEKTQPS LYSATFLEDI 5280
IIDLVHKFCS LLIITEDSKK NEMAELDIMG LALKLANSLI REFKKSDIKV LPNAEKMFSF 5340
PPIDKETVDK ISNFVYEQFI EKCTSHDIQK GDESNIAIGM IAALTQKAIS AFRIQPLFSG 5400
DWSSTFFSFL NPDNITQRVQ HLPQNTFTQI SRCAKENQLS LPDQSYKDTS STPDCKNMMS 5460
TLEINRGTMN RKKSFKTKDT SVKKGDIQNP VLSSINAIMK SGMINLTSGL ATGVTNKKEV 5520
DENKVGICTQ KHSENVSKVT STTTVKSKDT QEPNLSETFN NNEIEKKRNL IPTDKKGKDD 5580
EIYTHFSLII DDTEYEKEVL GSDSEIGYKK KIDNARESSF KKDDKLFQLS SLKSKRNLGT 5640
TTDTLEIRIR TSSNEGRRDS PTQTCRDEEH HSDYEHVQNV IENIFEDVLE LSSSPEPAYY 5700
SKLSYDQSPP GDNVLNVIQE ISRDSAQSVT TKKVSSSTNK NISAKEKEEE EREKEKVREE 5760
IKSEPSKPDD PQNQRESKPG IFPAKFLEDV ITEMVKQLIF SSIPETQIQD RCQNVSDKQN 5820
QAKLYDTAMK LINSLLKEFS DAQIKVFRPD KGNQFPGGKV SSVPKVPPRY KEPTTDEAPS 5880
SIKIKSADKM PPMHKMMRKP SSDKIPSIDK TLVNKVVHSS VCNILNDYGS QDSIWKNINS 5940
NGENLARRLT SAVINEIFQR QVNLIFCDEV SVSACLPLES KDVVKKVQKL AQTASKECQT 6000
SSPYTIILPH KFLENVISAL FSKIFSTISS TKTKEPEDNL STELNFLQMK LVSAVATEIS 6060
QDKYMTIQYV ETLQSDDDEI IQLVVQSVYN NLLPQFGSQE IIQNCVTSGC KILSENIVDL 6120
VLREVASNQL QSYFCGELTP HQCVEVENIV EKILKDVFQT TDVPLPKPSH ADKLSYNIIE 6180
EIAVKFLSKL LSIFPKVHKE RTKSLETDMQ KITSKVLNSV QEFISKSKIK LVPPTKESPT 6240
VPVADNATIE NIVNSIYTSV LKHSGSYTSV FKDLMGKSNV LSDTIGFLMV NAISNSEFQP 6300
QVEEEVSNSE LVLEAVKIME KVIKIIDELK SKEKSSSRKG LTLDAKLLEE VLALFLAKLI 6360
RLPSSSSKDE KNLSKTELNK IASQLSKLVT AEISRSSISL IASDPEEHCL NPENTERIYQ 6420
VVDSVYSNIL QQSGTNKEFY YDIKDTNTAF PKKVASLIID GVSSFPLDTI NSTISNADLS 6480
GELDVNRIVQ KAQEHAFNVI PELEQEKLDQ NLSEEESPIK IVPHVGKKPV KIDPKIISEH 6540
LAVISIKTQP LEKLKQECLK RTGHSIAELR RASISGRNYS LGSPDLEKRK TERRTSLDKT 6600
GRLDVKPLEA VARNSFQNIR KPDITKVELL KDVQSKNDLI VRLVAHDIDQ VYLENYIKEE 6660
RDSDEDEVVL TQTFAKEEGI KVFEDQVKEV KKPIQSKLSP KSTLSTSSLK KFLSLSKCCQ 6720
TTASANIEST EAISNQVIES KETHVKRAVA ELDMATPKTM PETASSSWEE KPQCKKEEKN 6780
LVTEPTHYFI HRIMSSSSYN QEDLISSTGE AEDCHSDPSA KILEESSQEQ KPEHGNSVKF 6840
ITIFERSKDV LGSANPSKEV ISETPKPDVS KQGSKMLTKM SSTLSKVFSQ CNTNISRSSS 6900
PAHQDEH 6907 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS