| Tag | Content |
|---|
| CPLM ID | CPLM-015419 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kin of IRRE-like protein 2 |
Protein Synonyms/Alias | Kin of irregular chiasm-like protein 2; Nephrin-like protein 3 |
Gene Name | KIRREL2 |
Gene Synonyms/Alias | NEPH3; UNQ5827/PRO19646 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 263 | VTGYRWAKGGSPVLG | ubiquitination | [1] | | 547 | SASFSEQKNLMRIPG | ubiquitination | [1] | | 675 | RAFTSYIKPTSFGPP | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | DOMAIN 24 118 Ig-like C2-type 1.
DOMAIN 123 222 Ig-like C2-type 2.
DOMAIN 227 307 Ig-like C2-type 3.
DOMAIN 312 394 Ig-like C2-type 4.
DOMAIN 398 501 Ig-like C2-type 5.
MOTIF 149 151 Cell attachment site (Potential).
CARBOHYD 143 143 N-linked (GlcNAc...) (Potential).
CARBOHYD 301 301 N-linked (GlcNAc...) (Potential).
CARBOHYD 484 484 N-linked (GlcNAc...) (Potential).
DISULFID 45 103 By similarity.
DISULFID 146 204 By similarity.
DISULFID 248 291 By similarity.
DISULFID 333 375 By similarity.
DISULFID 419 485 By similarity. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 708 AA |
Protein Sequence | MLRMRVPALL VLLFCFRGRA GPSPHFLQQP EDLVVLLGEE ARLPCALGAY WGLVQWTKSG 60
LALGGQRDLP GWSRYWISGN AANGQHDLHI RPVELEDEAS YECQATQAGL RSRPAQLHVL 120
VPPEAPQVLG GPSVSLVAGV PANLTCRSRG DARPTPELLW FRDGVLLDGA TFHQTLLKEG 180
TPGSVESTLT LTPFSHDDGA TFVCRARSQA LPTGRDTAIT LSLQYPPEVT LSASPHTVQE 240
GEKVIFLCQA TAQPPVTGYR WAKGGSPVLG ARGPRLEVVA DASFLTEPVS CEVSNAVGSA 300
NRSTALDVLF GPILQAKPEP VSVDVGEDAS FSCAWRGNPL PRVTWTRRGG AQVLGSGATL 360
RLPSVGPEDA GDYVCRAEAG LSGLRGGAAE ARLTVNAPPV VTALHSAPAF LRGPARLQCL 420
VFASPAPDAV VWSWDEGFLE AGSQGRFLVE TFPAPESRGG LGPGLISVLH ISGTQESDFS 480
RSFNCSARNR LGEGGAQASL GRRDLLPTVR IVAGVAAATT TLLMVITGVA LCCWRHSKAS 540
ASFSEQKNLM RIPGSSDGSS SRGPEEEETG SREDRGPIVH TDHSDLVLEE KGTLETKDPT 600
NGYYKVRGVS VSLSLGEAPG GGLFLPPPSP LGPPGTPTFY DFNPHLGMVP PCRLYRARAG 660
YLTTPHPRAF TSYIKPTSFG PPDLAPGTPP FPYAAFPTPS HPRLQTHV 708 |
Gene Ontology | GO:0016021; C:integral to membrane; NAS:UniProtKB. GO:0005886; C:plasma membrane; TAS:Reactome. GO:0036057; C:slit diaphragm; IEA:Compara. GO:0007155; P:cell adhesion; NAS:UniProtKB. GO:0016337; P:cell-cell adhesion; IEA:Compara. GO:0001933; P:negative regulation of protein phosphorylation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |