CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035352
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Myo6 
Protein Synonyms/Alias
  
Gene Name
 Myo6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
139DKAFRDMKVLKMSQSacetylation[1]
408TVIKVPLKVEQANSAacetylation[1]
715HELYNMYKKYMPEKLacetylation[1]
838PRIDGLVKVGTLKKRacetylation[1]
893MTREQIQKEYDALVKacetylation[1]
900KEYDALVKSSEDLLSacetylation[1]
1040GPAVQATKAAAGTKKubiquitination[2]
1052TKKHDLSKWKYAELRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1258 AA 
Protein Sequence
MEDGKPVWAP HPTDGFQMGN IVDIGPDSLT IEPLNQKGKT FLALINQVFP AEEDSKKDVE 60
DNCSLMYLNE ATLLHNVKVR YSKDRIYTYV ANILIAVNPY FDIPKIYSSD TIKSYQGKSL 120
GTMPPHVFAI ADKAFRDMKV LKMSQSIIVS GESGAGKTEN TKFSKILDRI LWGQDIDDRI 180
VEANPLLEAF GNAKTVRNNN SSRFGKFVEI HFNEKSSVVG GFVSHYLLEK SRICVQGKEE 240
RNYHIFYRLC AGASEDIREK LHLSSPDNFR YLNRGCTRYF ANKETDKQIL QNRKSPEYVK 300
AGSLKDPLLD PWRFYQDVHS HEKNRFMMKK NDLFRVVAGV LHLGNIDFEE AGSTSGGCNL 360
KNKSAPSLEY CAELLGLDQD DLRVSLTTRV MLTTAGGTKG TVIKVPLKVE QANSARDALA 420
KTVYSHLFDH VVDRVNQCFP FETSSYFIGV LDIAGFEYFE HNSFEQFCIN YCNEKLQQFF 480
NERILKENPN TFEASDIVSS LQMFLYLEID LIEVKLVGIL DILDEENRLP QPSDQHFTSV 540
VHQKHKDHFR LTIPRKSKLA VHRNLRDDEG FIIRHFAYGR VLLVRRQSSG RKNNDALHMS 600
LESLICESRD KFIRALFESS TNNNKDTKQK AGKLSFISVG NKFKTQLNLL LDKLRSTGAS 660
FIRCIKPNLK MTSHHFEGAQ ILSQLQCSGM VSVLDLMQGG FPSRASFHEL YNMYKKYMPE 720
KLARLDPRLF CKALFKALGL NEVDYKFGLT KVFFRPGKFA EFDQIMKSDP DHLAELVKRV 780
NLWLVCSRWK KVQWCSLSVI KLKNKIKYRA EACIKMQKTI RMWLCKRRHK PRIDGLVKVG 840
TLKKRLDKFN EVVSALKDGK PEVNRQIKDL EISIDALMAK IKSTMMTREQ IQKEYDALVK 900
SSEDLLSALQ KKKQQEEEAE RLRRIQEEME KERKRREEDE QRRRKEEEER RMKLEMEVKR 960
KQEEEERKKR EDDEKRIQAE VEAQLARQRE EESQQQAVLA QECRDRELAL RIAQNESELI 1020
SDEAQGDTAL RRGPAVQATK AAAGTKKHDL SKWKYAELRD TINTSCDIEL LAACREEFHR 1080
RLKVYHAWKS KNKKRNTETE QRAPKSVTDY DFAPFLNNSP QQNPAAQLPA RQQEIEMNRQ 1140
QRFFRIPFIR PADQYKDPQN KKKGWWYAHF DGPWIARQME LHPDKPPILL VAGKDDMEMC 1200
ELNLEETGLT RKRGAEILPR QFEEIWERCG GIQYLQSAIE SRQARPTYAT AMLQNLLK 1258 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:RGD.
 GO:0030139; C:endocytic vesicle; IDA:RGD.
 GO:0005794; C:Golgi apparatus; IDA:RGD.
 GO:0005902; C:microvillus; IDA:RGD.
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0032587; C:ruffle membrane; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro.
 GO:0042493; P:response to drug; IDA:RGD. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR001609; Myosin_head_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00063; Myosin_head 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
  
PRINTS
 PR00193; MYOSINHEAVY.