CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein FAM118A 
Protein Synonyms/Alias
  
Gene Name
 FAM118A 
Gene Synonyms/Alias
 C22orf8 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MDSVEKTTNRSEQubiquitination[1]
17RSEQKSRKFLKSLIRubiquitination[1]
174LDLKDKTKVLEWARGacetylation[2]
334CQDCAKRKLEENGIEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 357 AA 
Protein Sequence
MDSVEKTTNR SEQKSRKFLK SLIRKQPQEL LLVIGTGVSA AVAPGIPALC SWRSCIEAVI 60
EAAEQLEVLH PGDVAEFRRK VTKDRDLLVV AHDLIRKMSP RTGDAKPSFF QDCLMEVFDD 120
LEQHIRSPVV LQSILSLMDR GAMVLTTNYD NLLEAFGRRQ NKPMESLDLK DKTKVLEWAR 180
GHMKYGVLHI HGLYTDPCGV VLDPSGYKDV TQDAEVMEVL QNLYRTKSFL FVGCGETLRD 240
QIFQALFLYS VPNKVDLEHY MLVLKENEDH FFKHQADMLL HGIKVVSYGD CFDHFPGYVQ 300
DLATQICKQQ SPDADRVDST TLLGNACQDC AKRKLEENGI EVSKKRTQSD TDDAGGS 357 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS