CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-024036
UniProt Accession
RN215_HUMAN
;
Q9Y6U7
;
A6NEL1
Genbank Protein ID
AC004997
Genbank Nucleotide ID
AAD43187.1
Protein Name
RING finger protein 215
Protein Synonyms/Alias
Gene Name
RNF215
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
129
AQFHQEN
K
GSGPQAY
ubiquitination
[1]
138
SGPQAYP
K
ALVQQMR
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
ZN_FING 325 366 RING-type; atypical.
CARBOHYD 186 186 N-linked (GlcNAc...) (Potential).
Keyword
Complete proteome; Glycoprotein; Membrane; Metal-binding; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Zinc; Zinc-finger.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
377 AA
Protein Sequence
MGPAARPALR SPPPPPPPPP SPLLLLLPLL PLWLGLAGPG AAADGSEPAA GAGRGGARAV 60
RVDVRLPRQD ALVLEGVRIG SEADPAPLLG GRLLLMDIVD AEQEAPVEGW IAVAYVGKEQ 120
AAQFHQENKG SGPQAYPKAL VQQMRRALFL GASALLLLIL NHNVVRELDI SQLLLRPVIV 180
LHYSSNVTKL LDALLQRTQA TAEITSGESL SANIEWKLTL WTTCGLSKDG YGGWQDLVCL 240
GGSRAQEQKP LQQLWNAILL VAMLLCTGLV VQAQRQASRQ SQRELGGQVD LFKRRVVRRL 300
ASLKTRRCRL SRAAQGLPDP GAETCAVCLD YFCNKQWLRV LPCKHEFHRD CVDPWLMLQQ 360
TCPLCKFNVL GNRYSDD 377
Gene Ontology
GO:0016021
; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270
; F:zinc ion binding; IEA:InterPro.
Interpro
IPR001841
; Znf_RING.
IPR013083
; Znf_RING/FYVE/PHD.
Pfam
PF13639
; zf-RING_2
SMART
SM00184
; RING
PROSITE
PS00518
; ZF_RING_1
PS50089
; ZF_RING_2
PRINTS