CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009715
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 
Protein Synonyms/Alias
  
Gene Name
 Gng3 
Gene Synonyms/Alias
 Gngt3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
2******MKGETPVNSubiquitination[1]
24RKMVEQLKIEASLCRubiquitination[1]
36LCRIKVSKAAADLMTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. 
Sequence Annotation
 MOD_RES 5 5 Phosphothreonine.
 MOD_RES 9 9 Phosphoserine.
 MOD_RES 72 72 Cysteine methyl ester (By similarity).
 LIPID 72 72 S-geranylgeranyl cysteine (By  
Keyword
 Cell membrane; Complete proteome; Direct protein sequencing; Lipoprotein; Membrane; Methylation; Phosphoprotein; Prenylation; Reference proteome; Transducer. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 75 AA 
Protein Sequence
MKGETPVNST MSIGQARKMV EQLKIEASLC RIKVSKAAAD LMTYCDAHAC EDPLITPVPT 60
SENPFREKKF FCALL 75 
Gene Ontology
 GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0007186; P:G-protein coupled receptor signaling pathway; ISA:MGI. 
Interpro
 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 
Pfam
 PF00631; G-gamma 
SMART
 SM00224; GGL 
PROSITE
 PS50058; G_PROTEIN_GAMMA 
PRINTS
 PR00321; GPROTEING.