UniProt Accession

 NDUS4_MOUSE; Q9CXZ1; Q9WUB1 

Genbank Protein ID

 AK011124; AF124785 

Genbank Nucleotide ID

 BAB27417.2; AAD30474.1 

Protein Name

 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 

Protein Synonyms/Alias

 Complex I-18 kDa; CI-18 kDa; Complex I-AQDQ; CI-AQDQ; NADH-ubiquinone oxidoreductase 18 kDa subunit 

Gene Name

 Ndufs4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
150	WSYDVEEKKVPKPKS	acetylation	[1]
154	VEEKKVPKPKSKSYG	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. 

Sequence Annotation

  

Keyword

 Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 175 AA 

Protein Sequence

Gene Ontology

 GO:0005747; C:mitochondrial respiratory chain complex I; IDA:MGI.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:MGI.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0001932; P:regulation of protein phosphorylation; ISO:MGI. 

Interpro

 IPR006885; NADH_UbQ_FeS_4_mit. 

Pfam

 PF04800; ETC_C1_NDUFA4 

SMART

  

PROSITE

  

PRINTS