CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016522
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lysophosphatidic acid receptor 6 
Protein Synonyms/Alias
 LPA receptor 6; LPA-6; Oleoyl-L-alpha-lysophosphatidic acid receptor; P2Y purinoceptor 5; P2Y5; Purinergic receptor 5 
Gene Name
 Lpar6 
Gene Synonyms/Alias
 P2ry5; P2y5 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
334QHNLQTLKNKIFDNEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Binds to oleoyl-L-alpha-lysophosphatidic acid (LPA). Intracellular cAMP is involved in the receptor activation. Important for the maintenance of hair growth and texture (By similarity). 
Sequence Annotation
 LIPID 284 284 S-palmitoyl cysteine (By similarity).
 CARBOHYD 5 5 N-linked (GlcNAc...) (Potential).
 CARBOHYD 162 162 N-linked (GlcNAc...) (Potential).
 CARBOHYD 163 163 N-linked (GlcNAc...) (Potential).
 CARBOHYD 262 262 N-linked (GlcNAc...) (Potential).
 DISULFID 89 168 Potential.  
Keyword
 Cell membrane; Complete proteome; Disulfide bond; G-protein coupled receptor; Glycoprotein; Lipoprotein; Membrane; Palmitate; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 344 AA 
Protein Sequence
MVSSNGSQCP YDDSFKYTLY GCMFSMVFVL GLISNCVAIY IFICALKVRN ETTTYMINLA 60
MSDLLFVFTL PFRIFYFATR NWPFGDLLCK ISVMLFYTNM YGSILFLTCI SVDRFLAIVY 120
PFKSKTLRTK RNAKIVCIAV WFTVMGGSAP AVFFQSTHSQ GNNTSEACFE NFPAATWKTY 180
LSRIVIFIEI VGFFIPLILN VTCSSMVLRT LNKPVTLSRS KMNKTKVLKM IFVHLVIFCF 240
CFVPYNINLI LYSLMRTQTF VNCSVVAAVR TMYPITLCIA VSNCCFDPIV YYFTSDTIQN 300
SIKMKNWSVR RSDSRFSEVQ GTENFIQHNL QTLKNKIFDN ESAI 344 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro. 
Interpro
 IPR000276; GPCR_Rhodpsn.
 IPR017452; GPCR_Rhodpsn_7TM.
 IPR002188; P2Y5_purnocptor. 
Pfam
 PF00001; 7tm_1 
SMART
  
PROSITE
 PS00237; G_PROTEIN_RECEP_F1_1
 PS50262; G_PROTEIN_RECEP_F1_2 
PRINTS
 PR00237; GPCRRHODOPSN.
 PR01067; P2Y5ORPHANR.