UniProt Accession

 QCR6_RAT; Q5M9I5 

Genbank Protein ID

 BC086954 

Genbank Nucleotide ID

 AAH86954.1 

Protein Name

 Cytochrome b-c1 complex subunit 6, mitochondrial 

Protein Synonyms/Alias

 Complex III subunit 6; Complex III subunit VIII; Cytochrome c1 non-heme 11 kDa protein; Mitochondrial hinge protein; Ubiquinol-cytochrome c reductase complex 11 kDa protein 

Gene Name

 Uqcrh 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
17	LTGSGDPKEEEEEEL	acetylation	[1]
83	RDHCVAHKLFKSLK*	acetylation	[1]
86	CVAHKLFKSLK****	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 (By similarity). 

Sequence Annotation

 MOD_RES 40 40 N6-acetyllysine (By similarity).
 MOD_RES 61 61 Phosphothreonine (By similarity).
 MOD_RES 83 83 N6-acetyllysine (By similarity).
 DISULFID 35 79 By similarity.
 DISULFID 51 65 By similarity.  

Keyword

 Acetylation; Complete proteome; Disulfide bond; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Respiratory chain; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 89 AA 

Protein Sequence

Gene Ontology

 GO:0005750; C:mitochondrial respiratory chain complex III; IDA:RGD.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro.
 GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IC:RGD.
 GO:0051291; P:protein heterooligomerization; IDA:RGD. 

Interpro

 IPR003422; Cyt_b-c1_6.
 IPR023184; Ubol_cytC_Rdtase_hinge_dom. 

Pfam

 PF02320; UCR_hinge 

SMART

  

PROSITE

  

PRINTS