UniProt Accession

 J3QLR6_HUMAN; J3QLR6 

Genbank Protein ID

 AC127537 

Genbank Nucleotide ID

  

Protein Name

 Protein flightless-1 homolog 

Protein Synonyms/Alias

  

Gene Name

 FLII 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
121	DDDAEYMKHTRLFRC	ubiquitination	[1]
132	LFRCSNEKGYFAVTE	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 185 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR007123; Gelsolin_dom.
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR007122; Villin/Gelsolin. 

Pfam

 PF00626; Gelsolin
 PF12799; LRR_4 

SMART

  

PROSITE

 PS51450; LRR 

PRINTS

 PR00597; GELSOLIN.