UniProt Accession

 A1AG_RAT; P02764 

Genbank Protein ID

 J00696; V01216; M11329; M10614 

Genbank Nucleotide ID

 AAA40699.1; CAA24527.1; AAA40700.1; AAA40701.1 

Protein Name

 Alpha-1-acid glycoprotein 

Protein Synonyms/Alias

 Orosomucoid; OMD 

Gene Name

 Orm1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
124	FAHLIVLKKHGTFML	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction. 

Sequence Annotation

 CARBOHYD 25 25 N-linked (GlcNAc...) (Potential).
 CARBOHYD 34 34 N-linked (GlcNAc...) (Potential).
 CARBOHYD 76 76 N-linked (GlcNAc...) (Potential).
 CARBOHYD 94 94 N-linked (GlcNAc...) (Potential).
 CARBOHYD 104 104 N-linked (GlcNAc...) (Potential).
 CARBOHYD 134 134 N-linked (GlcNAc...) (Potential).
 DISULFID 91 183 By similarity.  

Keyword

 Acute phase; Complete proteome; Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 205 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0008144; F:drug binding; IDA:RGD.
 GO:0002438; P:acute inflammatory response to antigenic stimulus; IEP:RGD.
 GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
 GO:0071385; P:cellular response to glucocorticoid stimulus; IEP:RGD.
 GO:0071378; P:cellular response to growth hormone stimulus; IEP:RGD.
 GO:0071300; P:cellular response to retinoic acid; IEP:RGD.
 GO:0002439; P:chronic inflammatory response to antigenic stimulus; IEP:RGD.
 GO:0031100; P:organ regeneration; IEP:RGD.
 GO:0002682; P:regulation of immune system process; IEA:InterPro.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0032496; P:response to lipopolysaccharide; IEP:RGD.
 GO:0033197; P:response to vitamin E; IEP:RGD.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 

Interpro

 IPR001500; A1A_glycop.
 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR000566; Lipocln_cytosolic_FA-bd_dom. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00213; LIPOCALIN 

PRINTS

 PR00708; A1AGLPROTEIN.