CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MEP-1, isoform A 
Protein Synonyms/Alias
 MEP-1, isoform B; MEP-1, isoform C; MEP-1, isoform D; MEP-1, isoform E; MEP-1, isoform F; MEP-1, isoform G 
Gene Name
 MEP-1 
Gene Synonyms/Alias
 CG1244; Dmel_CG1244 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
78ELLSAGGKDISKEDVacetylation[1]
1123AANDSLLKPLKINDEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1152 AA 
Protein Sequence
MTEVDVVLPE GVAEPTTKLA SASSSPKQSK PSADDVEQQV TTVEDDEEQV VEEQQEEDVH 60
LPEAPSNEKL ELLSAGGKDI SKEDVAQASP QAPVADEIME VDGTEDVEEN EVENDDEDSQ 120
ITSSSSKEPK LDEEDEEATT NGDGDHEPED EDDAQKIGST AENSCEAEDP LGAVTVPDDE 180
LASGKKAHLD GEESVASEGV VEEEPPAKQE NGFGASPNQK ENGQASIAEA RAAIAPSDGG 240
VVNLDEDSDE EMEDITEHKE PAKPTEKAAK PASSSGGESS DDAVLIASDS DTESAAPPPP 300
VKKLPPVVKA IPPPPVQDDE DDDDDDDCVV IEDDTPLSIS PSGKRKSDLD DLQLQQPSHK 360
RQRSSTPSGM GQLTIKDARS LMPLDGSPSS VSGPRDSIYP VTITNAVTGA ATNLGVVPPK 420
LVPMAGGMSA SPVQLNPPTL SLTGLPSMTN NANLLPGLTD DMFVLEAPSF IVPYIYEKPP 480
RENICEVVKA IETKYALSAE DLAEADKGDE FDMMTEQNKE DKPADQADES GKKKKKKRGD 540
DESWSEQSDD DDDEDDDDDS ESGVRTKVLI KEANDDLSAL KVAIKPAAAL ATAGGVSVNN 600
PGGNKPGQEN YFESPLGKFF MDIGVGLVQE YVQSDLLRLQ KRKMRKAQVQ NSKEFEMAIN 660
ALSGNLQASK TKNAPFKFRM KRCEFCNFKS ESAMAMANHY ETPHMNGVLY KCNFCTFEIR 720
NATEIVYHME AVHNIKARLI KPLPYHQCPN CGFEDNGKAK LARHQPVCAK KFRPELNLAP 780
PNDWEAPAKI PRIKPRHGLV GTATAYQAMA AQAAAQKAAL ANIQQQQAAA QARNNLQAAA 840
LAAQNAAKMR QRAPQPPKQN IVRNPAPVRG GNAMNAGLSL PNSYQLAAGQ LVQASKKPMA 900
GQPSISITPL PRQSSVGAGA GASSSKAPQA AAGMKPGQSP SGNNKAQFVI CEICDGYIKD 960
LEQLRNHMQW MHKVKIHPKM IYNRPPLNCQ KCQFRFFTDQ GLERHLLGSH GLVTSSMQEA 1020
ANKGKDAGRC PVCGRMYQWK LLNHVSRDHH MTLKPAHLSY KCTVCTATFG MYKQFETHVY 1080
TAHSTVARKA MDSKKNSAQS SGSGSGAGMS RSSLGAANDS LLKPLKINDE ITIIPQPASK 1140
PRITNMESHV ID 1152 
Gene Ontology
 GO:0016581; C:NuRD complex; IPI:FlyBase.
 GO:0005700; C:polytene chromosome; IDA:FlyBase.
 GO:0003682; F:chromatin binding; IDA:FlyBase.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
  
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1 
PRINTS