CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025045
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GDP-mannose 4, 6-dehydratase 
Protein Synonyms/Alias
 Protein Gmds; RCG44147 
Gene Name
 Gmds 
Gene Synonyms/Alias
 rCG_44147 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
70GRIEHLYKNPQAHIEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 372 AA 
Protein Sequence
MAHAPASCRR YPGSGDGEMG KLRKVALITG ITGQDGSYLA EFLLEKGYEV HGIVRRSSSF 60
NTGRIEHLYK NPQAHIEGNM KLHYGDLTDS TCLVKIINEV KPTEIYNLGA QSHVKISFDL 120
AEYTADVDGV GTLRLLDAIK TCGLINSVKF YQASTSELYG KVQEIPQKET TPFYPRSPYG 180
AAKLYAYWIV VNFREAYNLF AVNGILFNHE SPRRGANFVT RKISRSVAKI YLGQLECFSL 240
GNLDAKRDWG HAKDYVEAMW LMLQNDEPED FVIATGEVHS VREFVEKSFM HIGKTIVWEG 300
KNENEVGRCK ETGKIHVTVD LKYYRPTEVD FLQGDCSKAQ QKLNWKPRVA FDELVREMVQ 360
ADVELMRTNP NA 372 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008446; F:GDP-mannose 4,6-dehydratase activity; ISS:UniProtKB.
 GO:0070401; F:NADP+ binding; ISS:UniProtKB.
 GO:0042351; P:'de novo' GDP-L-fucose biosynthetic process; ISS:UniProtKB.
 GO:0019673; P:GDP-mannose metabolic process; ISS:UniProtKB.
 GO:0007219; P:Notch signaling pathway; ISS:UniProtKB. 
Interpro
 IPR001509; Epimerase_deHydtase.
 IPR006368; GDP_Man_deHydtase.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF01370; Epimerase 
SMART
  
PROSITE
  
PRINTS