CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010015
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Glycerol kinase 
Protein Synonyms/Alias
 ATP:glycerol 3-phosphotransferase; Glycerokinase; GK 
Gene Name
 glpK 
Gene Synonyms/Alias
 MPN_050; MP104 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
341AESDFYAKLAQKEEQacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity). 
Sequence Annotation
 NP_BIND 419 423 ATP (By similarity).
 BINDING 15 15 Substrate (By similarity).
 BINDING 19 19 ATP (By similarity).
 BINDING 85 85 Substrate (By similarity).
 BINDING 138 138 Substrate (By similarity).
 BINDING 251 251 Substrate (By similarity).
 BINDING 273 273 ATP (By similarity).
 BINDING 317 317 ATP; via carbonyl oxygen (By similarity).  
Keyword
 ATP-binding; Complete proteome; Glycerol metabolism; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
MDLKQQYILA LDEGTSSCRT IVFDKDLNQV AIAQNEFNQF FPKSGWVEQD PLEIWSVQLA 60
TMQSAKNKAQ IKSNNIAAVG ITNQRETIVL WNKENGLPVY NAIVWQDQRT ASLCDKLNQD 120
TKIKEFVKKH TGLPINPYFS ATKIAWILEN VPLAQKMLKE DKLLAGTIDT WLIWKLTGGK 180
MHVTDVSNAS RTLLFDITTM TWSQELGDIF KVPLSILPKV MPSNAHFGDI VPSHWSTSAT 240
GMVPIRGVAG DQQAALFGQL CVEPAMVKNT YGTGCFMLMN IGNELKYSQH NLLTTVAWQL 300
ENQKPVYALE GSVFVAGAAL KWLRDSLKVM YSAAESDFYA KLAQKEEQEV VFVPAFTGLG 360
APYWDASARG AIFGIEANTK REHLVKATLE AIAFQANDLI KAMASDLNSS IKKIKADGGA 420
CNSNYLMQFQ ADIANLEVII PKNVETTTMG AAFLAGLAVN YWKDTKQLEK LTGIAKQFKS 480
QMNQTVREKK SKRWNEAVKR TLKWASLD 508 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
 GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP. 
Interpro
 IPR018485; Carb_kinase_FGGY_C.
 IPR018483; Carb_kinase_FGGY_CS.
 IPR018484; Carb_kinase_FGGY_N.
 IPR005999; Glycerol_kin. 
Pfam
 PF02782; FGGY_C
 PF00370; FGGY_N 
SMART
  
PROSITE
 PS00933; FGGY_KINASES_1
 PS00445; FGGY_KINASES_2 
PRINTS