Tag | Content |
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CPLM ID | CPLM-018560 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 |
Protein Synonyms/Alias | Alpha 2,3-ST 4; Beta-galactoside alpha-2,3-sialyltransferase 4; Alpha 2,3-sialyltransferase IV; Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; ST3Gal IV; ST3GalIV; Sialyltransferase 4C; SIAT4-C |
Gene Name | St3gal4 |
Gene Synonyms/Alias | Siat4c |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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91 | YELPFGTKGSEDLLL | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids (By similarity). |
Sequence Annotation | CARBOHYD 61 61 N-linked (GlcNAc...) (Potential). CARBOHYD 131 131 N-linked (GlcNAc...) (Potential). CARBOHYD 310 310 N-linked (GlcNAc...) (Potential). CARBOHYD 329 329 N-linked (GlcNAc...) (Potential). DISULFID 120 273 By similarity. |
Keyword | Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 333 AA |
Protein Sequence | MTSKSHWKLL ALALVLVVVM VWYSISREDR YIEFFYFPIS EKKEPCFQGE AERQASKIFG 60 NRSREQPIFL QLKDYFWVKT PSTYELPFGT KGSEDLLLRV LAITSYSIPE SIKSLECRRC 120 VVVGNGHRLR NSSLGGVINK YDVVIRLNNA PVAGYEGDVG SKTTIRLFYP ESAHFDPKIE 180 NNPDTLLVLV AFKAMDFHWI ETILSDKKRV RKGFWKQPPL IWDVNPKQVR ILNPFFMEIA 240 ADKLLSLPIQ QPRKIKQKPT TGLLAITLAL HLCDLVHIAG FGYPDASNKK QTIHYYEQIT 300 LKSMAGSGHN VSQEAIAIKR MLEMGAVKNL TYF 333 |
Gene Ontology | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. GO:0030173; C:integral to Golgi membrane; IEA:InterPro. GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; IDA:MGI. GO:0047288; F:monosialoganglioside sialyltransferase activity; IEA:Compara. GO:0006486; P:protein glycosylation; IDA:MGI. |
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Pfam | |
SMART | |
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PRINTS | |