CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BolA-like protein 2 
Protein Synonyms/Alias
  
Gene Name
 BOLA2; BOLA2B 
Gene Synonyms/Alias
 BOLA2A; My016 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
43RVLVVSAKFEGKPLLubiquitination[1]
47VSAKFEGKPLLQRHRacetylation[2]
47VSAKFEGKPLLQRHRubiquitination[1, 3, 4]
73HIHAFEQKTLTPDQWubiquitination[1, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 MOD_RES 1 1 N-acetylmethionine.  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 86 AA 
Protein Sequence
MELSAEYLRE KLQRDLEAEH VEVEDTTLNR CSCSFRVLVV SAKFEGKPLL QRHRLVNACL 60
AEELPHIHAF EQKTLTPDQW ARERQK 86 
Gene Ontology
  
Interpro
 IPR002634; BolA. 
Pfam
 PF01722; BolA 
SMART
  
PROSITE
  
PRINTS