CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020637
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RPA-interacting protein 
Protein Synonyms/Alias
  
Gene Name
 Rpain 
Gene Synonyms/Alias
 Rip 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
14SPHRLLYKQVGSPHWubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Sumoylation mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism (By similarity). 
Sequence Annotation
 ZN_FING 137 212 RIP-type.
 REGION 164 180 Mediates nuclear export (By similarity).  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Ubl conjugation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 219 AA 
Protein Sequence
MAESSGSPHR LLYKQVGSPH WKETFRQGCL ERMRNSRHRL LNKYRQAAGS TPGTASDRLL 60
VQEVMEEEWA SLQSVENCPE ALLQLELPLD LAVLQDIEQE LCNEEKSIIS EYEEDLEFDE 120
SCLRRMLAEW EANSLICPVC IKYNLRIMNS VVTCPCGLHI PVHSTDLTEQ KLRACLEENV 180
NEHSVHCPHT PVFSVTGGTE EKPSLLMNCL TCDTWAVIL 219 
Gene Ontology
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:Compara.
 GO:0006281; P:DNA repair; IEA:Compara.
 GO:0006261; P:DNA-dependent DNA replication; IEA:Compara.
 GO:0006606; P:protein import into nucleus; IEA:Compara.
 GO:0009411; P:response to UV; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS