UniProt Accession

 TPRA1_HUMAN; Q86W33; A8MVB8; D3DNA9; Q8WZ24; Q96AJ6; Q9P2R4 

Genbank Protein ID

 AB037108; AF289568; AC023593; AC084035; CH471052; CH471052; BC017058; BC050711 

Genbank Nucleotide ID

 BAA89782.1; AAL55752.1; EAW79343.1; EAW79344.1; AAH17058.1; AAH50711.1 

Protein Name

 Transmembrane protein adipocyte-associated 1 

Protein Synonyms/Alias

 Integral membrane protein GPR175; Transmembrane protein 227 

Gene Name

 TPRA1 

Gene Synonyms/Alias

 GPR175; TMEM227; PP6566 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
289	GFFGSEPKILFSYKC	ubiquitination	[1, 2]
295	PKILFSYKCQVDETE	ubiquitination	[3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

 CARBOHYD 11 11 N-linked (GlcNAc...) (Potential).
 CARBOHYD 23 23 N-linked (GlcNAc...) (Potential).
 CARBOHYD 361 361 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 373 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
 GO:0007568; P:aging; TAS:ProtInc.
 GO:0006629; P:lipid metabolic process; TAS:ProtInc. 

Interpro

 IPR018781; Uncharacterised_TM-40. 

Pfam

 PF10160; Tmemb_40 

SMART

  

PROSITE

  

PRINTS