UniProt Accession

 H3BNC0_HUMAN; H3BNC0 

Genbank Protein ID

 AC020978; AC099521; CH471092 

Genbank Nucleotide ID

 EAW83232.1 

Protein Name

 Protein arginine N-methyltransferase 7 

Protein Synonyms/Alias

 Protein arginine methyltransferase 7, isoform CRA_e 

Gene Name

 PRMT7 

Gene Synonyms/Alias

 hCG_28114 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
2	******MKIFCSRAN	ubiquitination	[1]
42	YADMLHDKDRNVKYY	ubiquitination	[1]
47	HDKDRNVKYYQGIRA	ubiquitination	[1, 2]
109	AAVKIVEKNGFSDKI	ubiquitination	[1, 3]
115	EKNGFSDKIKVINKH	ubiquitination	[1]
121	DKIKVINKHSTEVTV	ubiquitination	[1]
451	KANHLEDKINIIEKR	ubiquitination	[2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Methyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 567 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0008276; F:protein methyltransferase activity; IEA:InterPro. 

Interpro

 IPR025799; Arg_MeTrfase.
 IPR025801; Arg_MeTrfase_PMTR7_chr.
 IPR010456; Ribosomal-L11_MeTrfase_PrmA. 

Pfam

 PF06325; PrmA 

SMART

  

PROSITE

 PS51629; SAM_PRMT7_1 

PRINTS