UniProt Accession

 GSTM2_RAT; P08010 

Genbank Protein ID

 J02592; M13590; J03914 

Genbank Nucleotide ID

 AAA41285.1; AAA42351.1; AAA41296.1 

Protein Name

 Glutathione S-transferase Mu 2 

Protein Synonyms/Alias

 GST 4-4; GSTM2-2; Glutathione S-transferase Yb-2; GST Yb2 

Gene Name

 Gstm2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
31	TDTSYEDKKYSMGDA	acetylation	[1]
32	DTSYEDKKYSMGDAP	acetylation	[1]
124	SPDFERKKPEYLEGL	acetylation	[1]
134	YLEGLPEKMKLYSEF	acetylation	[1]
144	LYSEFLGKQPWFAGN	acetylation	[1]
199	KKISDYMKSGRFLSK	acetylation	[1]
206	KSGRFLSKPIFAKMA	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process. 

Sequence Annotation

 DOMAIN 2 88 GST N-terminal.
 DOMAIN 90 214 GST C-terminal.
 REGION 7 8 Glutathione binding.
 REGION 43 50 Glutathione binding.
 REGION 59 60 Glutathione binding.
 REGION 72 73 Glutathione binding.
 BINDING 116 116 Substrate (By similarity).  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Olfaction; Reference proteome; Sensory transduction; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:RGD.
 GO:0005886; C:plasma membrane; IDA:RGD.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0004364; F:glutathione transferase activity; IMP:RGD.
 GO:0042803; F:protein homodimerization activity; IDA:RGD.
 GO:0007568; P:aging; IEP:RGD.
 GO:0014070; P:response to organic cyclic compound; IEP:RGD.
 GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
 GO:0006805; P:xenobiotic metabolic process; TAS:RGD. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR003081; GST_mu.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00043; GST_C
 PF02798; GST_N 

SMART

  

PROSITE

 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS

 PR01267; GSTRNSFRASEM.