CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038563
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Formin-1 
Protein Synonyms/Alias
  
Gene Name
 Fmn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1213REYLQPFKDKLEEFFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1332 AA 
Protein Sequence
MEGTHCTLQL HNPIAELCYI SFYLPKGEVR GFSYKGTVTL DRSNNAFHNC YQVREGPDIT 60
SLSQQPNEHP GDIFFKQTPT KNILTELYKL TAEKERLLDS LLRSDNILGV SMGSQEGKLQ 120
ELSVILATGD EYFQSAGNWR RELPVSSLIR RSTQENKKPR RSGRRRESPE ELRQKRTRRK 180
GRGCQESAFQ MGKDQVCSSS SLSFRARPNL RLLEERGNLV PRGTLTSSLR RRESCPANIL 240
RTPDADLAFG NSGRTSEDTD LEGPLSPDSS PTEVGDADVG GQLKSSHQQE PPQPNVSESH 300
GKHAGAERWS SRTRKSKSLE RTCSKKPVSK VVAKIQEPSA PVKRIVRAHH DGKGRVAYGP 360
ETQTEFIPKA DFLTLPGGET ETHSSGRLEE EQPGIKSLRS SAPERASITK EPASTEAAVN 420
KVLRKVIESE KLDEATEGKR LGFSLNTRAT HTFPETRSQR KAGLPQSGHK FLLLDLPHTV 480
GPDSPQPKCD EKKPTPQVPT ALGMVFNNSS PQSSAHKRLS PVPSPLSPRC PSPQQHHRIL 540
LLPPLPSEGE VVFNEYPSRK NDVSSGFPSA DTLEPSSTTK VTETKGASPT SLRASQTWLV 600
SEEASEKGLG PEKITAPPQH QLPPEYQAAI LHLKREHKEE IETLQAQFEL KTFHIRGEHA 660
LVTARLEEAI ENLKQQLGKR REGCEEMRDV CISTDDDCSP KAFRNVCIQT DRETFLKPCD 720
AESKATRSSQ IVPKKLTISL TQLSPSKDSK DIHAPFQTRE GTSSSSQHKI SPPAPPTPPP 780
LPPPLIPPPP PLPPGLGPLP PAPPIPPVCP VSPPPPPPPP PPTPVPPSDG PPPPPPPPPP 840
LPNVLALPNS GGPPPPPPPP PPGLAPPPPP GLSFGLSSSS SQYPRKPAIE PSCPMKPLYW 900
TRIQINDKSQ DAAPTLWDSL EEPHIRDTSE FEYLFSKDTT QQKKKPLSEA YEKKNKVKKI 960
IKLLDGKRSQ TVGILISSLH LEMKDIQQAI FTVDDSVVDL ETLAALYENR AQEDELTKIR 1020
KYYETSKEED LKLLDKPEQF LHELAQIPNF AERAQCIIFR AVFSEGITSL HRKVEIVTRA 1080
SKGLLHMKSV KDILALILAF GNYMNGGNRT RGQADGYSLE ILPKLKDVKS RDNGMNLVDY 1140
VVKYYLRYYD QEAGTDKSVF PLPEPQDFFL ASQVKFEDLL KDLRKLKRQL EASEQQMKLV 1200
CKESPREYLQ PFKDKLEEFF KKAKKEHKME ESHLENAQKS FETTVGYFGM KPKTGEKEVT 1260
PSYVFMVWFE FCSDFKTIWK RESKNISKER LKMAQASVSK LTSEKKVETK KINPTASLKE 1320
RLRQKEASVA TN 1332 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:InterPro.
 GO:0005912; C:adherens junction; IPI:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
 GO:0035136; P:forelimb morphogenesis; IMP:MGI.
 GO:0010467; P:gene expression; IMP:MGI.
 GO:0035137; P:hindlimb morphogenesis; IMP:MGI.
 GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.
 GO:0051127; P:positive regulation of actin nucleation; IDA:MGI.
 GO:0048705; P:skeletal system morphogenesis; IMP:MGI. 
Interpro
 IPR003104; Actin-bd_FH2/DRF_autoreg.
 IPR015425; FH2_actin-bd.
 IPR001265; Formin. 
Pfam
 PF02181; FH2 
SMART
 SM00498; FH2 
PROSITE
 PS51444; FH2 
PRINTS
 PR00828; FORMIN.