| Tag | Content |
|---|
| CPLM ID | CPLM-015622 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inhibitor of nuclear factor kappa-B kinase-interacting protein |
Protein Synonyms/Alias | I kappa-B kinase-interacting protein; IKBKB-interacting protein; IKK-interacting protein |
Gene Name | IKBIP |
Gene Synonyms/Alias | IKIP |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 212 | KVEKNTVKNIGDLLS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Target of p53/TP53 with pro-apoptotic function. |
Sequence Annotation | CARBOHYD 144 144 N-linked (GlcNAc...).
CARBOHYD 328 328 N-linked (GlcNAc...). |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 350 AA |
Protein Sequence | MSEVKSRKKS GPKGAPAAEP GKRSEGGKTP VARSSGGGGW ADPRTCLSLL SLGTCLGLAW 60
FVFQQSEKFA KVENQYQLLK LETNEFQQLQ SKISLISEKW QKSEAIMEQL KSFQIIAHLK 120
RLQEEINEVK TWSNRITEKQ DILNNSLTTL SQDITKVDQS TTSMAKDVGL KITSVKTDIR 180
RISGLVTDVI SLTDSVQELE NKIEKVEKNT VKNIGDLLSS SIDRTATLRK TASENSQRIN 240
SVKKTLTELK SDFDKHTDRF LSLEGDRAKV LKTVTFANDL KPKVYNLKKD FSRLEPLVND 300
LTLRIGRLVT DLLQREKEIA FLSEKISNLT IVQAEIKDIK DEIAHISDMN 350 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:HGNC. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0006917; P:induction of apoptosis; IMP:HGNC. GO:0010165; P:response to X-ray; IEP:HGNC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |