CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010232
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized aldolase LsrF 
Protein Synonyms/Alias
  
Gene Name
 lsrF 
Gene Synonyms/Alias
 yneB; b1517; JW1510 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
20FRTDQPQKNIPFTLKacetylation[1]
165QLVDAGMKVGMPTMAacetylation[1]
178MAVTGVGKDMVRDQRacetylation[1]
209IKTYYVEKGFERIVAacetylation[1]
290YELYLSEKQ******acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Could be involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle (By similarity). 
Sequence Annotation
 ACT_SITE 203 203 Schiff-base intermediate with substrate  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Lyase; Reference proteome; Schiff base. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 291 AA 
Protein Sequence
MADLDDIKDG KDFRTDQPQK NIPFTLKGCG ALDWGMQSRL SRIFNPKTGK TVMLAFDHGY 60
FQGPTTGLER IDINIAPLFE HADVLMCTRG ILRSVVPPAT NRPVVLRASG ANSILAELSN 120
EAVALSMDDA VRLNSCAVAA QVYIGSEYEH QSIKNIIQLV DAGMKVGMPT MAVTGVGKDM 180
VRDQRYFSLA TRIAAEMGAQ IIKTYYVEKG FERIVAGCPV PIVIAGGKKL PEREALEMCW 240
QAIDQGASGV DMGRNIFQSD HPVAMMKAVQ AVVHHNETAD RAYELYLSEK Q 291 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR002915; DeoC/FbaB/lacD_aldolase. 
Pfam
 PF01791; DeoC 
SMART
  
PROSITE
  
PRINTS