CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036145
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 CDGSH iron-sulfur domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 CISD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
84KDSLINLKIQKENPKacetylation[1]
105IEDLCLTKAAYCRCWubiquitination[2, 3]
141NVGPLILKKKEV***acetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 145 AA 
Protein Sequence
MPQGLLSSEL SPVSFRGKIP GFCREGAELG TGQSLSSPVL LIALFSEWLR LLPFLGVLAL 60
LGYLAVRPFL PKKKQQKDSL INLKIQKENP KVVNEINIED LCLTKAAYCR CWRSKTFPAC 120
DGSHNKHNEL TGDNVGPLIL KKKEV 145 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:HPA.
 GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro. 
Interpro
 IPR018967; FeS-contain_CDGSH-typ.
 IPR006622; FeS-contain_CDGSH-typ_subfam.
 IPR019610; FeS-contain_mitoNEET_N. 
Pfam
 PF10660; MitoNEET_N
 PF09360; zf-CDGSH 
SMART
 SM00704; ZnF_CDGSH 
PROSITE
  
PRINTS