| Tag | Content |
|---|
| CPLM ID | CPLM-007909 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nucleolar pre-ribosomal-associated protein 2 |
Protein Synonyms/Alias | Unhealthy ribosome biogenesis protein 2 |
Gene Name | URB2 |
Gene Synonyms/Alias | NPA2; YJR041C; J1622 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 206 | LRYFAQTKNSASSNQ | ubiquitination | [1] | | 907 | RLLWNSAKSFSTISQ | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Required for 27S pre-rRNA processing. Has an early role during 60S ribosomal subunit assembly. |
Sequence Annotation | |
Keyword | Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1174 AA |
Protein Sequence | MGDLTEELSI PDNAQDLSKL LRSTSTKPHQ IAEIVSKFDK LETYFPKKEI FVLDLLIDRL 60
NNGNLDDFKT SEHTWIIFTR LLDAINDPIS IKKLLKKLKT VPVMIRTFFL WPKDKLLTRS 120
VSFIKAFFAI NDYLIVNFSV EESFQLLEHA INGLSSCPTT DFALSYLQDA CNLTHVDNIT 180
TTDNKIATCY CKHMLLPSLR YFAQTKNSAS SNQSFIRLSH FMGKFLLQPR IDYMKLNKKF 240
VQENASEITD DMAYYYFATF VTFLSKDNFA QLEVIFTILG AKKPSLECRF LNLLSESKKT 300
VSQEFLEALL LEMLASTDES GVLSLIPIIL KLDIEVAIKH IFRLLELIQL ENLNDPLFSS 360
HIWDLIIQSH ANARELSDFF AKINEYCSRK GPDSYFLINH PAYVKSITKQ LFTLSSLQWK 420
NLLQALLDQV NHDSTNRVPL YLIRICLEGL SEGASRATLD EVKPILSQVF TLESFNNSLQ 480
WDLKYHIMEV YDDIVPAEEL EKIDYVLSSN IFDTTSADVE ELFFYCFKLR EYISFDLSDA 540
KKKFMRHFEI LDEERKSNLS YSVVSKFATL VNNNFTREQI SSLIDSLLLN STNLSSLLKN 600
DDIFEETNIT YALINKLASS YHQTFALEAL IQIPIQCINK NVRVALINNL TCESFCLDSA 660
TRECLLHLLS SPTFKSNIET NFYELCEKTI MSPEMAISET GDEKKEIEDK ISIFEKVWTN 720
HLSQAKEPVS EKFLESGYDI VKQSMSLSNG DSKLIIAGFT IAKFLKPDNK HRDIQGMAIS 780
YAVKILENYS ENFESETIPL FRISMSTLYK IITTGQGDIS KHKSRILDIF SKIMLRYHSK 840
KVYHAPEEQE MFLVHSLLTE NKLEYIFAEY LNIEHTDKCD SALGFCLEES LKQGPDAFNR 900
LLWNSAKSFS TISQPCAEKF VRVFIIMSKR IARDNNLGHH LFVIALLEAY TYCDIEKFGY 960
KSYLLLFNAI KEFLVSKPWL FSQYCIEMLL PFCLKTLAFI VNHESTDEIN EGFINIIEVI 1020
DHMLLVHRFK FSNRHHLFNS VLCQILEIIA IHDGTLCANS ADAVARLITN YCEPYNVSNA 1080
QNGQKNNLSS KISLIKQSIR KNVLVVLTKY IQLSITTQFS LNIKKSLQPG IHAIFDILSQ 1140
NELNQLNAFL DTPGKQYFKA LYLQYKKVGK WRED 1174 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |