CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039270
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ARF GTPase-activating protein GIT1 
Protein Synonyms/Alias
  
Gene Name
 Git1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
33GRHISIVKHLRHSAWacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 754 AA 
Protein Sequence
PDPGWASISR GVLVCDECCS VHRSLGRHIS IVKHLRHSAW PPTLLQMVHT LASNGANSIW 60
EHSLLDPAQV QSGRRKANPQ DKVHPIKSEF IRAKYQMLAF VHKLPCRDDD GVTAKDLSKQ 120
LHSSVRTGNL ETCLRLLSLG AQANFFHPEK GTTPLHVAAK AGQTLQAELL VVYGADPGSP 180
DVNGRTPIDY ARQAGHHELA ERLVECQYEL TDRLAFYLCG RKPDHKNGHY IIPQMADRSR 240
QKCMSQRLDL GKMAKAAKKK LQALSNRLFE ELAMDVYDEV DRRENDAVWL ATQNHSTLVT 300
ERSAVPFLPV NPEYSATRNQ GRQKLARFNA REFATLIIDI LSEAKRRQQG KSLSSPTDNL 360
ELSARNQSDL DDQHDYDSVA SDEDTDQEPL PSAGATRNNR ARSMDSSDLS DGAVTLQEYL 420
ELKKALATSE AKVQQLMKVN SSLSDELRKL QREIHKLQAE NLQLRQPPGP VPVPSLPSER 480
AEHTLMGPGG STHRRDRQAF SMYEPGSALK PFGGAPGDEL ATRLQPFHST ELEDDAIYSV 540
HVPAGLYRIR KGVSASSVTF TPSSPLLSSS QEGSRHASKL SRHGSGAESD YENTQSGEPL 600
LGLEGKRFLE LSKEDELHAE LESLDGDPDP GLPSTEDVIL KTEQVTKNIQ ELLRAAQEFK 660
HDSFVPCSEK IHLAVTEMAS LFPKRPALEP VRSSLRLLNA SAYRLQSECR KTVPPEPGAP 720
VDFQLLTQQV IQCAYDIAKA AKQLVTITTR EKKQ 754 
Gene Ontology
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001164; ArfGAP.
 IPR022018; GIT1_C.
 IPR013724; GIT_SHD. 
Pfam
 PF12796; Ank_2
 PF01412; ArfGap
 PF12205; GIT1_C
 PF08518; GIT_SHD 
SMART
 SM00248; ANK
 SM00105; ArfGap
 SM00555; GIT 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50115; ARFGAP 
PRINTS