| Tag | Content |
|---|
| CPLM ID | CPLM-032090 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rho guanine nucleotide exchange factor 7 |
Protein Synonyms/Alias | cDNA FLJ56152, highly similar to Rho guanine nucleotide exchange factor 7 |
Gene Name | ARHGEF7 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 148 | SEKPVSPKSGTLKSP | ubiquitination | [1] | | 673 | VDTVYALKDEVQELR | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 721 AA |
Protein Sequence | MKTFDANDLY QGQNFNKVLS SLVTLNKVTA DIGLGSDSVC ARPSSHRIKS FDSLGSQSLH 60
TRTSKLFQGQ YRSLDMTDNS NNQLVVRAKF NFQQTNEDEL SFSKGDVIHV TRVEEGGWWE 120
GTLNGRTGWF PSNYVREVKA SEKPVSPKSG TLKSPPKGFD TTAINKSYYN VVLQNILETE 180
NEYSKELQTV LSTYLRPLQT SEKLSSANIS YLMGNLEEIC SFQQMLVQSL EECTKLPEAQ 240
QRVGGCFLNL MPQMKTLYLT YCANHPSAVN VLTEHSEELG EFMETKGASS PGILVLTTGL 300
SKPFMRLDKY PTLLKELERH MEDYHTDRQD IQKSMAAFKN LSAQCQEVRK RKELELQILT 360
EAIRNWEGDD IKTLGNVTYM SQVLIQCAGS EEKNERYLLL FPNVLLMLSA SPRMSGFIYQ 420
GKLPTTGMTI TKLEDSENHR NAFEISGSMI ERILVSCNNQ QDLQEWVEHL QKQTKVTSVG 480
NPTIKPHSVP SHTLPSHPVT PSSKHADSKP APLTPAYHTL PHPSHHGTPH TTINWGPLEP 540
PKTPKPWSLS CLRPAPPLRP SAALCYKEDL SKSPKTMKKL LPKRKPERKP SDEEFASRKS 600
TAALEEDAQI LKVIEAYCTS AKTRQTLNSS SRKESAPQVL LPEEEKIIVE ETKSNGQTVI 660
EEKSLVDTVY ALKDEVQELR QDNKKMKKSL EEEQRARKDL EKLVRKVLKN MNDPAWDETN 720
L 721 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |