CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038249
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sulfated glycoprotein 1 
Protein Synonyms/Alias
  
Gene Name
 Psap 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
440GGFCEVCKKLVLYLEacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 551 AA 
Protein Sequence
MGGSGQTLVM PLTSPVQDPK TCSGGSAVLC RDVKTAVDCG AVKHCQQMVW SKPTAKSLPC 60
DICKTVVTEA GNLLKDNATQ EEILHYLEKT CEWIHDSSLS ASCKEVVDSY LPVILDMIKG 120
EMSNPGEVCS ALNLCQSLQE YLAEQNQKQL ESNKIPEVDM ARVVAPFMSN IPLLLYPQDH 180
PRSQPQPKAN EDVCQDCMKL VSDVQTAVKT NSSFIQGFVD HVKEDCDRLG PGVSDICKNY 240
VDQYSEVCVQ MLMHMQPKEI CVLAGFCNEV KRVPMKTLVP ATETIKNILP ALEMMDPYEQ 300
NLVQAHNVIL CQTCQFVMNK FSELIVNNAT EELLVKGLSN ACALLPDPAR TKCQEVVGTF 360
GPSLLDIFIH EVNPSSLCGV IGLCAARPEL VEALEQPAPA IVSALLKEPT PPKQPAQPKQ 420
SALPAHVPPQ KNGGFCEVCK KLVLYLEHNL EKNSTKEEIL AALEKGCSFL PDPYQKQCDD 480
FVAEYEPLLL EILVEVMDPG FVCSKIGVCP SAYKLLLGTE KCVWGPSYWC QNMETAARCN 540
AVDHCKRHVW N 551 
Gene Ontology
 GO:0005764; C:lysosome; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0071310; P:cellular response to organic substance; IMP:MGI.
 GO:0060742; P:epithelial cell differentiation involved in prostate gland development; IMP:MGI.
 GO:0060736; P:prostate gland growth; IMP:MGI.
 GO:0019216; P:regulation of lipid metabolic process; IMP:MGI.
 GO:0043408; P:regulation of MAPK cascade; IMP:MGI.
 GO:0006665; P:sphingolipid metabolic process; IEA:InterPro. 
Interpro
 IPR003119; SapA.
 IPR007856; SapB_1.
 IPR008138; SapB_2.
 IPR008373; Saposin.
 IPR011001; Saposin-like.
 IPR021165; Saposin_chordata.
 IPR008139; SaposinB. 
Pfam
 PF02199; SapA
 PF05184; SapB_1
 PF03489; SapB_2 
SMART
 SM00162; SAPA
 SM00741; SapB 
PROSITE
 PS51110; SAP_A
 PS50015; SAP_B 
PRINTS
 PR01797; SAPOSIN.