UniProt Accession

 RSSA1_YEAST; P32905; D6VUZ7 

Genbank Protein ID

 M88277; Z72999; BK006941 

Genbank Nucleotide ID

 AAB05643.1; CAA97241.1; DAA08308.1 

Protein Name

 40S ribosomal protein S0-A 

Protein Synonyms/Alias

 Nucleic acid-binding protein NAB1A 

Gene Name

 RPS0A 

Gene Synonyms/Alias

 NAB1; NAB1A; YST1; YGR214W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
52	VHVINVGKTWEKLVL	ubiquitination	[1]
56	NVGKTWEKLVLAARI	acetylation	[2]
88	FGQRAVLKFAAHTGA	acetylation	[2]
88	FGQRAVLKFAAHTGA	ubiquitination	[1, 3]
167	IPCNNRGKHSIGLIW	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. 

Sequence Annotation

 MOD_RES 2 2 N-acetylserine.  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; Ribosome biogenesis; rRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 252 AA 

Protein Sequence

Gene Ontology

 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IMP:SGD.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000028; P:ribosomal small subunit assembly; IMP:SGD.
 GO:0006407; P:rRNA export from nucleus; IGI:SGD. 

Interpro

 IPR001865; Ribosomal_S2.
 IPR018130; Ribosomal_S2_CS.
 IPR027498; Ribosomal_S2_euk.
 IPR005707; Ribosomal_S2_euk/arc.
 IPR023591; Ribosomal_S2_flav_dom. 

Pfam

 PF00318; Ribosomal_S2 

SMART

  

PROSITE

 PS00962; RIBOSOMAL_S2_1
 PS00963; RIBOSOMAL_S2_2 

PRINTS

 PR00395; RIBOSOMALS2.