CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037353
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Uncharacterized protein C4orf21 
Protein Synonyms/Alias
  
Gene Name
 C4orf21 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
152PENIVTYKNRERNAMubiquitination[1, 2]
203LLTNEPVKRDSLASHubiquitination[1, 2]
333DDVNSNLKDLSLQKIubiquitination[1, 2, 3]
777VETAREGKQYWNPRNubiquitination[1]
864QQKTVKKKIKPTLPLmethylation[4]
866KTVKKKIKPTLPLRImethylation[4]
866KTVKKKIKPTLPLRIubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 915 AA 
Protein Sequence
MFQAILYDDK GACLESLFLK CLEVKPGDDL ESDRYLITVE EVKVAGAIGI VKQNVNKEAP 60
ELNSRTFISS GRSLGCQPSG LKRKFTGFQG PRQVPKKMVI MESGESAASH EAKKTGPTIF 120
SPFCSMPPLF PTVGKKDVNN ILADPENIVT YKNRERNAMD FSSVFSPSFQ INPEVLCEEN 180
YFCSPVNSGN KLSDSLLTNE PVKRDSLASH YSGVSQNIRS KAQILALLKS ESSSSCEELN 240
SEMTEHFPQK QPQGSLKIAT KPKYLIQQEE CAEMKSTENL YYQHQSENTM RNKSRWAMYL 300
SSQSSPIHSS TVDGNDTERK PKAQEDDVNS NLKDLSLQKI IQFVETYAEE RKKYNVDQSV 360
GNNDPSWNQE VKLEIPSFNE SSSLQVTCSS AENDGILSES DIQEDNKIPF NQNDKGCIKG 420
SVLIKENAQE VNTCGTLEKE YEQSESSLPE LKHLQIESSN NSRISDDITD MISESKMDNE 480
SLNSIHESLS NVTQPFLEVT FNLNNFETSD TEEESQESNK ISQDSESWVK DILVNDGNSC 540
FQKRSENTNC EEIEGEHLPF LTSVSDKPTV TFPVKETLPS QFCDKTYVGF DMGICKTENT 600
GKEIEEYSDT LSNFESFKWT DAVYGDNKED ANKPIQEVRI NYDFALPPNK SKGINMNLHI 660
PHIQNQIAEN SNLFSEDAQP QPFILGSDLD KNDEHVLPST SSSDNSVQLL NTNQNHYECI 720
ALDKSNTHIS NSLFYPLGKK HLISKDTEAH ISEPEDLGKI RSPPPDHVEV ETAREGKQYW 780
NPRNSSELSG LVNTISILKS LCEHSTALDS LEILKKKNTV FQQGTQQTYE PDSPPEVRKP 840
FITVVSPKSP HLHKDSQQKT VKKKIKPTLP LRIFINVSRF FCVQLKKMVR LMYINSFISF 900
PLNIVVLSYI INNSS 915 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS