CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025356
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Tbc1d17 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
23YLHTSARKHQDPDSLubiquitination[1]
303LQNVPELKNRIFSGGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 652 AA 
Protein Sequence
MEGSSYRVVF EKGGVYLHTS ARKHQDPDSL IAGVIRVVEK DSDVFLHWAP VEEAGDPTQI 60
LFKKDPSRGE PSTSEEEPTF DPGYEPDWAV ISTVRPQPHL AEPRKGAEPS SSRSSWAFSV 120
SLGELKSIRR SKPGLSWAYL VLVTQAGGSL PALHFHRGGT RALLRVLSRY LLLASSPQDS 180
RLYLVFPQDP SALSDSFHHL QLFDQDSSNV VSRFLQDPYS TTFSSFSRVT NFFRGALQPH 240
PEGASSPNLP PLPDDEPEPG FEVISCVELG QRPTVERAPP VTEEEWNRYV GPEGRLQNVP 300
ELKNRIFSGG LSPGLRREAW KFLLGYLSWE SSAEEHKAHV RKKTDEYFRM KLQWKSVSAE 360
QERRNSLLHG YRSLIERDVS RTDRTNKFYE GPENPGLSLL HDILLTYCMY HFDLGYVQGM 420
SDLLSPILFV VQNEVDAFWC FCGFMELVHG NFEESQETMK RQLGQLLLLL RVLDQPLCDF 480
LDSQDSGSLC FCFRWLLIWF KREFPFPDVL RLWEVLWTGL PGPNLHLLVA CAILDMERDT 540
LMLSGFGSNE ILKHINELTM KLSVEDVLTR AEALYRQLTA CPELPHNVQE ILGLAQPEEP 600
SSPSPPVSPM PLSPTRAPLP PPLPEEVIPQ PDSSLEILPE DEDGAWLLAR CI 652 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
 GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. 
Interpro
 IPR021935; DUF3548.
 IPR000195; Rab-GTPase-TBC_dom. 
Pfam
 PF12068; DUF3548
 PF00566; RabGAP-TBC 
SMART
 SM00164; TBC 
PROSITE
 PS50086; TBC_RABGAP 
PRINTS