UniProt Accession

 NECP1_RAT; P69682; Q4QR67 

Genbank Protein ID

 AABR03032682; BC097496 

Genbank Nucleotide ID

 AAH97496.1 

Protein Name

 Adaptin ear-binding coat-associated protein 1 

Protein Synonyms/Alias

 NECAP endocytosis-associated protein 1; NECAP-1 

Gene Name

 Necap1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
37	GYRASDWKLDQPDWT	acetylation	[1]
59	KGKIAYIKLEDKVSG	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Involved in endocytosis (By similarity). 

Sequence Annotation

 MOTIF 254 257 WXXF motif 1.
 MOTIF 274 277 WXXF motif 2.  

Keyword

 Cell membrane; Complete proteome; Cytoplasmic vesicle; Direct protein sequencing; Endocytosis; Membrane; Protein transport; Reference proteome; Repeat; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 277 AA 

Protein Sequence

Gene Ontology

 GO:0030125; C:clathrin vesicle coat; IEA:Compara.
 GO:0005905; C:coated pit; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR012466; NECAP-1.
 IPR011993; PH_like_dom. 

Pfam

 PF07933; DUF1681 

SMART

  

PROSITE

  

PRINTS