UniProt Accession

 RLA2_YEAST; P05319; D6W227 

Genbank Protein ID

 X06958; J03760; M26503; Z74781; AY692793; BK006948 

Genbank Nucleotide ID

 CAA30028.1; AAA34971.1; AAA34735.1; CAA99041.1; AAT92812.1; DAA10743.1 

Protein Name

 60S acidic ribosomal protein P2-alpha 

Protein Synonyms/Alias

 P2A; A2; L12EIB; L44; YP2alpha 

Gene Name

 RPP2A 

Gene Synonyms/Alias

 L12EIB; RPA2; RPL44; RPLA2; YOL039W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
2	******MKYLAAYLL	ubiquitination	[1, 2]
21	GNTPDATKIKAILES	ubiquitination	[1]
37	GIEIEDEKVSSVLSA	ubiquitination	[2]
48	VLSALEGKSVDELIT	acetylation	[3]
48	VLSALEGKSVDELIT	ubiquitination	[1]

Reference

 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Plays an important role in the elongation step of protein synthesis. 

Sequence Annotation

 MOD_RES 16 16 Phosphothreonine.
 MOD_RES 40 40 Phosphoserine.
 MOD_RES 43 43 Phosphoserine.
 MOD_RES 49 49 Phosphoserine.
 MOD_RES 96 96 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 106 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD.
 GO:0006414; P:translational elongation; ISS:SGD. 

Interpro

 IPR001813; Ribosomal_L10/L12.
 IPR027534; Ribosomal_L12. 

Pfam

 PF00428; Ribosomal_60s 

SMART

  

PROSITE

  

PRINTS