CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010140
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Thioredoxin 
Protein Synonyms/Alias
 Trx 
Gene Name
 trxA 
Gene Synonyms/Alias
 trx; MPN_263; MP570 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
6**MVTEIKSLKQLGEacetylation[1]
42ITGPEFAKAASEVSTacetylation[1]
80PTIVLFEKGQEKHRAacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
 Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). 
Sequence Annotation
 DOMAIN 2 102 Thioredoxin.
 DISULFID 30 33 Redox-active (By similarity).  
Keyword
 Complete proteome; Disulfide bond; Electron transport; Redox-active center; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MVTEIKSLKQ LGELFASNNK VIIDFWAEWC GPCKITGPEF AKAASEVSTV AFAKVNVDEQ 60
TDIAAAYKIT SLPTIVLFEK GQEKHRAIGF MPKAKIVQLV SQ 102 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0006662; P:glycerol ether metabolic process; IEA:InterPro. 
Interpro
 IPR005746; Thioredoxin.
 IPR012336; Thioredoxin-like_fold.
 IPR017937; Thioredoxin_CS.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS00194; THIOREDOXIN_1
 PS51352; THIOREDOXIN_2 
PRINTS
 PR00421; THIOREDOXIN.