Tag | Content |
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CPLM ID | CPLM-015185 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein tweety homolog 3 |
Protein Synonyms/Alias | mTTY3 |
Gene Name | Ttyh3 |
Gene Synonyms/Alias | Kiaa1691 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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508 | YTSSMRAKYLATSQP | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction (By similarity). |
Sequence Annotation | MOD_RES 504 504 Phosphoserine. CARBOHYD 126 126 N-linked (GlcNAc...) (Potential). CARBOHYD 144 144 N-linked (GlcNAc...) (Potential). CARBOHYD 351 351 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Calcium; Cell membrane; Chloride; Chloride channel; Complete proteome; Glycoprotein; Ion channel; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 524 AA |
Protein Sequence | MAGVSYAAPW WVSLLHRLPH FDLRWEATSS QFRPEDADYQ QALLLLGATA LACLALDLLF 60 LLFYSFWLCC RRRKTDEHLD ADCCCTAWCV IITTLVCSAG IAVGFYGNGE TSDGIHRATY 120 SLRHANRTVA GVQDRVWDTA AALNRTAEPN LQSLERQLAG RQEPLRAVQR LQTLLGTLLG 180 YTAAIPFWRN PGVSLEVLAE QVDLYDWYRW LGYLGLLLLD VIICLLVLVG LIRSSKGILV 240 GVCLLGVLAL VISWGALGLE LAVSVGSSDF CVDPDTFVTK MVEEHSVLSG DILQYYLACS 300 PRATNPFQQK LSGSHKALVE MQDVVAELLR NVPREHPATK DPLLRVQEVL NGTEVNLQHL 360 TALVDCRSLH LDYVQALTGF CYDGVEGLIY LALFSFVTAL MFSSIVCSIP HTWQQKRGPD 420 DDGEEETAPG PRQAHDSLYR VHMPSLYSCG SSYGSEASIP AAAHTVSNAP VTEYMSQNAN 480 FQNPRCENTP LIGRESPPPS YTSSMRAKYL ATSQPRPDSS GSGH 524 |
Gene Ontology | GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW. |
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