CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015185
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein tweety homolog 3 
Protein Synonyms/Alias
 mTTY3 
Gene Name
 Ttyh3 
Gene Synonyms/Alias
 Kiaa1691 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
508YTSSMRAKYLATSQPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction (By similarity). 
Sequence Annotation
 MOD_RES 504 504 Phosphoserine.
 CARBOHYD 126 126 N-linked (GlcNAc...) (Potential).
 CARBOHYD 144 144 N-linked (GlcNAc...) (Potential).
 CARBOHYD 351 351 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Calcium; Cell membrane; Chloride; Chloride channel; Complete proteome; Glycoprotein; Ion channel; Ion transport; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 524 AA 
Protein Sequence
MAGVSYAAPW WVSLLHRLPH FDLRWEATSS QFRPEDADYQ QALLLLGATA LACLALDLLF 60
LLFYSFWLCC RRRKTDEHLD ADCCCTAWCV IITTLVCSAG IAVGFYGNGE TSDGIHRATY 120
SLRHANRTVA GVQDRVWDTA AALNRTAEPN LQSLERQLAG RQEPLRAVQR LQTLLGTLLG 180
YTAAIPFWRN PGVSLEVLAE QVDLYDWYRW LGYLGLLLLD VIICLLVLVG LIRSSKGILV 240
GVCLLGVLAL VISWGALGLE LAVSVGSSDF CVDPDTFVTK MVEEHSVLSG DILQYYLACS 300
PRATNPFQQK LSGSHKALVE MQDVVAELLR NVPREHPATK DPLLRVQEVL NGTEVNLQHL 360
TALVDCRSLH LDYVQALTGF CYDGVEGLIY LALFSFVTAL MFSSIVCSIP HTWQQKRGPD 420
DDGEEETAPG PRQAHDSLYR VHMPSLYSCG SSYGSEASIP AAAHTVSNAP VTEYMSQNAN 480
FQNPRCENTP LIGRESPPPS YTSSMRAKYL ATSQPRPDSS GSGH 524 
Gene Ontology
 GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW. 
Interpro
 IPR006990; Tweety. 
Pfam
 PF04906; Tweety 
SMART
  
PROSITE
  
PRINTS