UniProt Accession

 D3YUI7_MOUSE; D3YUI7 

Genbank Protein ID

 AC140353 

Genbank Nucleotide ID

  

Protein Name

 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform 

Protein Synonyms/Alias

  

Gene Name

 Myl2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
27	NRDGFIDKNDLRDTF	ubiquitination	[1]
43	ALGRVNVKNEEIDEM	ubiquitination	[1]
72	TMFGEKLKGADPEET	ubiquitination	[1]
92	KVFDPEGKGSLKADY	ubiquitination	[1]
96	PEGKGSLKADYVREM	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Calcium; Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 115 AA 

Protein Sequence

Gene Ontology

 GO:0015629; C:actin cytoskeleton; IEA:Compara.
 GO:0030016; C:myofibril; IDA:MGI.
 GO:0005509; F:calcium ion binding; ISO:MGI.
 GO:0060048; P:cardiac muscle contraction; IGI:MGI.
 GO:0055003; P:cardiac myofibril assembly; IMP:MGI.
 GO:0003007; P:heart morphogenesis; IGI:MGI.
 GO:0042694; P:muscle cell fate specification; IMP:MGI.
 GO:0048747; P:muscle fiber development; IGI:MGI.
 GO:0030308; P:negative regulation of cell growth; IEA:Compara.
 GO:0009791; P:post-embryonic development; IGI:MGI.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Compara. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF13405; EF_hand_4 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS