CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017937
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 671 
Protein Synonyms/Alias
  
Gene Name
 ZNF671 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
381CGKFFSSKSNLIRHQubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 49 120 KRAB.
 ZN_FING 192 214 C2H2-type 1; degenerate.
 ZN_FING 285 307 C2H2-type 2.
 ZN_FING 313 335 C2H2-type 3.
 ZN_FING 341 363 C2H2-type 4.
 ZN_FING 369 391 C2H2-type 5.
 ZN_FING 397 419 C2H2-type 6.
 ZN_FING 425 447 C2H2-type 7.
 ZN_FING 451 473 C2H2-type 8.
 ZN_FING 479 501 C2H2-type 9.
 ZN_FING 507 529 C2H2-type 10.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 534 AA 
Protein Sequence
MLSPVSRDAS DALQGRKCLR PRSRRLPLPA AVRAHGPMAE LTDSARGCVV FEDVFVYFSR 60
EEWELLDDAQ RLLYHDVMLE NFALLASLGI AFSRSRAVMK LERGEEPWVY DQVDMTSATE 120
REAQRGLRPG CWHGVEDEEV SSEQSIFVAG VSEVRTLMAE LESHPCDICG PILKDTLHLA 180
KYHGGKARQK PYLCGACGKQ FWFSTDFDQH QNQPNGGKLF PRKEGRDSVK SCRVHVPEKT 240
LTCGKGRRDF SATSGLLQHQ ASLSSMKPHK STKLVSGFLM GQRYHRCGEC GKAFTRKDTL 300
ARHQRIHTGE RPYECNECGK FFSQSYDLFK HQTVHTGERP YECSECGKFF RQISGLIEHR 360
RVHTGERLYQ CGKCGKFFSS KSNLIRHQEV HTGARPYVCS ECGKEFSRKH TLVLHQRTHT 420
GERPYECSEC GKAFSQSSHL NVHWRIHSSD YECSRCGKAF SCISKLIQHQ KVHSGEKPYE 480
CSKCGKAFTQ RPNLIRHWKV HTGERPYVCS ECGREFIRKQ TLVLHQRVHA GEKL 534 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS