CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028742
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable ATP-dependent RNA helicase DDX58 
Protein Synonyms/Alias
  
Gene Name
 Ddx58 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
451DVSEELGKLFQIQNRubiquitination[1]
555EKLEELEKVSRDPSNubiquitination[1]
600RALVDALKKWIEENPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 707 AA 
Protein Sequence
MTAEQRQNLQ AFRDYIKKIL DPTYILSYMS SWLEDGYCGL CEAIESWDFQ KIEKLEEHRL 60
LLRRLEPEFK ATVDPNDILS ELSECLINQE CEEIRQIRDT KGRMAGAEKM AECLIRSDKE 120
NWPKVLQLAL EKDNSKFSEL WIVDKGFKRA ESKADEDDGA EASSIQIFIQ EEPECQNLSQ 180
NPGPPSEASS NNLHSPLKPR NYQLELALPA KKGKNTIICA PTGCGKTFVS LLICEHHLKK 240
FPCGQKGKVV FFANQIPVYE QQATVFSRYF ERLGYNIASI SGATSDSVSV QHIIEDNDII 300
ILTPQILVNN LNNGAIPSLS VFTLMIFDEC HNTSKNHPYN QIMFRYLDHK LGESRDPLPQ 360
VVGLTASVGV GDAKTAEEAM QHICKLCAAL DASVIATVRD NVAELEQVVY KPQKISRKVA 420
SRTSNTFKCI ISQLMKETEK LAKDVSEELG KLFQIQNREF GTQKYEQWIV GVHKACSVFQ 480
MADKEEESRV CKALFLYTSH LRKYNDALII SEDAQMTDAL NYLKAFFHDV REAAFDETER 540
ELTRRFEEKL EELEKVSRDP SNENPKLRDL YLVLQEEYHL KPETKTILFV KTRALVDALK 600
KWIEENPALS FLKPGILTGR GRTNRATGMT LPAQKCVLEA FRASGDNNIL IATSVADEGI 660
DIAECNLVIL YEYVGNVIKM IQTRGRGRAR DSKCFLLTSS ADVIEKE 707 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003690; F:double-stranded DNA binding; IDA:MGI.
 GO:0003725; F:double-stranded RNA binding; IDA:MGI.
 GO:0043330; P:response to exogenous dsRNA; IMP:MGI. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER 
PRINTS