UniProt Accession

 O88933_MOUSE; O88933 

Genbank Protein ID

 AL672275; AF085715; AF017735 

Genbank Nucleotide ID

 AAC35366.1; AAD01622.1 

Protein Name

 Homeobox protein SPX1 

Protein Synonyms/Alias

 Homeodomain protein EPX; Protein Esx1 

Gene Name

 Esx1 

Gene Synonyms/Alias

 Epx 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
5	***MESHKKCPCCYC	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 382 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
 GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.
 GO:0060713; P:labyrinthine layer morphogenesis; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0051726; P:regulation of cell cycle; IEA:Compara.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI. 

Interpro

 IPR017970; Homeobox_CS.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR000047; HTH_motif. 

Pfam

 PF00046; Homeobox 

SMART

 SM00389; HOX 

PROSITE

 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 

PRINTS

 PR00031; HTHREPRESSR.