CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028207
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FI03252p 
Protein Synonyms/Alias
 Pavarotti 
Gene Name
 pav 
Gene Synonyms/Alias
 pav-RA; CG1258; Dmel_CG1258 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
749RSRSAGDKWLEHRAAacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 887 AA 
Protein Sequence
MKAVPRTPMR VVPKTPRVHQ TVEKQRRDTS DKARDPVNVF CRVRPLQSDA DLTSLRVKNS 60
TTIALNPQDQ LLQHHKPHNG AQREVQYIFK HVFQPDATQQ DVYAAVAQPL VENLLKGRNS 120
LLFTYGVTGS GKTYTMTGNL RHRGIMPRCL DVLFRTISDY QAKKFVFKPD KLNGFEILSE 180
EDALLERQHE MNQRFAGSGR FAFRHKDSDP EIASQASVEP IPLLGLDEDN MYSVFVTYIE 240
IYNNSVYDLL EDSGIQKTLQ SKIIREDANR HMFVHGVTEV EVKTVEDALE VFQMGQKRKR 300
MGHTVLNAES SRSHSVFNIR LVQAPTDSQG ENVVQDRQNI TVSQLSLVDL AGSERSSRTK 360
NTGVRLREAG NINNSLMTLR TCLEYLRENQ LAASNGLAPK KVPYRDSKIT HMFKNYFDGE 420
GQVSMIVCIN PRIEDYDENM QVMKFAEMTQ EVQIARATPM KQDLGLTPGR RKANKLFKIA 480
VNNLNELGIP EAKDLEVDVG LVYSLGPDFP AYEMDSPEAQ IKIRELMHYL EQRIEKRKKL 540
RANLDIKCDS FRQMLMNLDR DNLQLRTELA SLKAVYKQER DRSAALEKKV RIHESSIDVL 600
NNTLSKQERQ IEELTFKLNE KENMLTQKEH EKEKQKKKFS SKLAVESDKN KREFELKLRE 660
QRVKLQERMR IKDEKLRLVS NILQSEDLPS LPRSQSSENI LNEKDRGAYT ARTEESSVPA 720
TRTDIYATPR HGAAAANNRH RRSRSAGDKW LEHRAANPVP LGTIMQPYLK NRKSVTKLTD 780
LKELTAHGTT KYCLVSQDAD TDGDVETKLY KGNVIPTCGG GAQVVFNDVE CLKQKSPVHS 840
PTRKRPSNGN ISALGGGAVP STVTSAQDVA SRCNLGIEGH SSKKSKI 887 
Gene Ontology
 GO:0005813; C:centrosome; NAS:FlyBase.
 GO:0005871; C:kinesin complex; ISS:FlyBase.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0030496; C:midbody; IDA:FlyBase.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0005819; C:spindle; NAS:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; ISS:FlyBase.
 GO:0000916; P:actomyosin contractile ring contraction; IMP:FlyBase.
 GO:0001709; P:cell fate determination; IMP:FlyBase.
 GO:0051298; P:centrosome duplication; IMP:FlyBase.
 GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; NAS:FlyBase.
 GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.
 GO:0032507; P:maintenance of protein location in cell; IMP:FlyBase.
 GO:0007018; P:microtubule-based movement; ISS:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0007422; P:peripheral nervous system development; NAS:FlyBase.
 GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.
 GO:0070507; P:regulation of microtubule cytoskeleton organization; IMP:FlyBase.
 GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.
 GO:0007224; P:smoothened signaling pathway; IGI:FlyBase.
 GO:0007525; P:somatic muscle development; IMP:FlyBase. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.