UniProt Accession

 M0R050_HUMAN; M0R050 

Genbank Protein ID

 AC011462 

Genbank Nucleotide ID

  

Protein Name

 Exosome complex component RRP46 

Protein Synonyms/Alias

  

Gene Name

 EXOSC5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
10	EETHTDAKIRAENGT	ubiquitination	[1, 2]
153	ALDSVERKLLMSSTK	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 197 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001247; ExoRNase_PH_dom1.
 IPR015847; ExoRNase_PH_dom2.
 IPR027408; PNPase/RNase_PH_dom.
 IPR020568; Ribosomal_S5_D2-typ_fold. 

Pfam

 PF01138; RNase_PH
 PF03725; RNase_PH_C 

SMART

  

PROSITE

  

PRINTS